Q5T200: Zinc finger CCCH domain-containing protein 13 {ECO:0000305}

General Information

Protein names	- Zinc finger CCCH domain-containing protein 13 {ECO:0000305}
Gene names	ZC3H13
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q5T200

9 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSKIRRKVTV ENTKTISDST SRRPSVFERL GPSTGSTAET QCRNWLKTGN CLYGNTCRFV
        70         80         90        100        110        120
HGPSPRGKGY SSNYRRSPER PTGDLRERMK NKRQDVDTEP QKRNTEESSS PVRKESSRGR
       130        140        150        160        170        180
HREKEDIKIT KERTPESEEE NVEWETNRDD SDNGDINYDY VHELSLEMKR QKIQRELMKL
       190        200        210        220        230        240
EQENMEKREE IIIKKEVSPE VVRSKLSPSP SLRKSSKSPK RKSSPKSSSA SKKDRKTSAV
       250        260        270        280        290        300
SSPLLDQQRN SKTNQSKKKG PRTPSPPPPI PEDIALGKKY KEKYKVKDRI EEKTRDGKDR
       310        320        330        340        350        360
GRDFERQREK RDKPRSTSPA GQHHSPISSR HHSSSSQSGS SIQRHSPSPR RKRTPSPSYQ
       370        380        390        400        410        420
RTLTPPLRRS ASPYPSHSLS SPQRKQSPPR HRSPMREKGR HDHERTSQSH DRRHERREDT
       430        440        450        460        470        480
RGKRDREKDS REEREYEQDQ SSSRDHRDDR EPRDGRDRRD ARDTRDRREL RDSRDMRDSR
       490        500        510        520        530        540
EMRDYSRDTK ESRDPRDSRS TRDAHDYRDR EGRDTHRKED TYPEESRSYG RNHLREESSR
       550        560        570        580        590        600
TEIRNESRNE SRSEIRNDRM GRSRGRVPEL PEKGSRGSRG SQIDSHSSNS NYHDSWETRS
       610        620        630        640        650        660
SYPERDRYPE RDNRDQARDS SFERRHGERD RRDNRERDQR PSSPIRHQGR NDELERDERR
       670        680        690        700        710        720
EERRVDRVDD RRDERARERD RERERDRERE RERERERDRE REKERELERE RARERERERE
       730        740        750        760        770        780
KERDRERDRD RDHDRERERE RERDREKERE REREERERER ERERERERER ERERERARER
       790        800        810        820        830        840
DKERERQRDW EDKDKGRDDR REKREEIRED RNPRDGHDER KSKKRYRNEG SPSPRQSPKR
       850        860        870        880        890        900
RREHSPDSDA YNSGDDKNEK HRLLSQVVRP QESRSLSPSH LTEDRQGRWK EEDRKPERKE
       910        920        930        940        950        960
SSRRYEEQEL KEKVSSVDKQ REQTEILESS RMRAQDIIGH HQSEDRETSD RAHDENKKKA
       970        980        990       1000       1010       1020
KIQKKPIKKK KEDDVGIERG NIETTSEDGQ VFSPKKGQKK KSIEKKRKKS KGDSDISDEE
      1030       1040       1050       1060       1070       1080
AAQQSKKKRG PRTPPITTKE ELVEMCNGKN GILEDSQKKE DTAFSDWSDE DVPDRTEVTE
      1090       1100       1110       1120       1130       1140
AEHTATATTP GSTPSPLSSL LPPPPPVATA TATTVPATLA ATTAAAATSF STSAITISTS
      1150       1160       1170       1180       1190       1200
ATPTNTTNNT FANEDSHRKC HRTRVEKVET PHVTIEDAQH RKPMDQKRSS SLGSNRSNRS
      1210       1220       1230       1240       1250       1260
HTSGRLRSPS NDSAHRSGDD QSGRKRVLHS GSRDREKTKS LEITGERKSR IDQLKRGEPS
      1270       1280       1290       1300       1310       1320
RSTSSDRQDS RSHSSRRSSP ESDRQVHSRS GSFDSRDRLQ ERDRYEHDRE RERERRDTRQ
      1330       1340       1350       1360       1370       1380
REWDRDADKD WPRNRDRDRL RERERERERD KRRDLDRERE RLISDSVERD RDRDRDRTFE
      1390       1400       1410       1420       1430       1440
SSQIESVKRC EAKLEGEHER DLESTSRDSL ALDKERMDKD LGSVQGFEET NKSERTESLE
      1450       1460       1470       1480       1490       1500
GDDESKLDDA HSLGSGAGEG YEPISDDELD EILAGDAEKR EDQQDEEKMP DPLDVIDVDW
      1510       1520       1530       1540       1550       1560
SGLMPKHPKE PREPGAALLK FTPGAVMLRV GISKKLAGSE LFAKVKETCQ RLLEKPKDAD
      1570       1580       1590       1600       1610       1620
NLFEHELGAL NMAALLRKEE RASLLSNLGP CCKALCFRRD SAIRKQLVKN EKGTIKQAYT
      1630       1640       1650       1660
SAPMVDNELL RLSLRLFKRK TTCHAPGHEK TEDNKLSQSS IQQELCVS

Isoforms

- Isoform 2 of Zinc finger CCCH domain-containing protein 13

Sequence View

        10         20         30         40         50         60
MSKIRRKVTV ENTKTISDST SRRPSVFERL GPSTGSTAET QCRNWLKTGN CLYGNTCRFV
        70         80         90        100        110        120
HGPSPRGKGY SSNYRRSPER PTGDLRERMK NKRQDVDTEP QKRNTEESSS PVRKESSRGR
       130        140        150        160        170        180
HREKEDIKIT KERTPESEEE NVEWETNRDD SDNGDINYDY VHELSLEMKR QKIQRELMKL
       190        200        210        220        230        240
EQENMEKREE IIIKKEVSPE VVRSKLSPSP SLRKSSKSPK RKSSPKSSSA SKKDRKTSAV
       250        260        270        280        290        300
SSPLLDQQRN SKTNQSKKKG PRTPSPPPPI PEDIALGKKY KEKYKVKDRI EEKTRDGKDR
       310        320        330        340        350        360
GRDFERQREK RDKPRSTSPA GQHHSPISSR HHSSSSQSGS SIQRHSPSPR RKRTPSPSYQ
       370        380        390        400        410        420
RTLTPPLRRS ASPYPSHSLS SPQRKQSPPR HRSPMREKGR HDHERTSQSH DRRHERREDT
       430        440        450        460        470        480
RGKRDREKDS REEREYEQDQ SSSRDHRDDR EPRDGRDRRD ARDTRDRREL RDSRDMRDSR
       490        500        510        520        530        540
EMRDYSRDTK ESRDPRDSRS TRDAHDYRDR EGRDTHRKED TYPEESRSYG RNHLREESSR
       550        560        570        580        590        600
TEIRNESRNE SRSEIRNDRM GRSRGRVPEL PEKGSRGSRG SQIDSHSSNS NYHDSWETRS
       610        620        630        640        650        660
SYPERDRYPE RDNRDQARDS SFERRHGERD RRDNRERDQR PSSPIRHQGR NDELERDERR
       670        680        690        700        710        720
EERRVDRVDD RRDERARERD RERERDRERE RERERERDRE REKERELERE RARERERERE
       730        740        750        760        770        780
KERDRERDRD RDHDRERERE RERDREKERE REREERERER ERERERERER ERERERARER
       790        800        810        820        830        840
DKERERQRDW EDKDKGRDDR REKREEIRED RNPRDGHDER KSKKRYRNEG SPSPRQSPKR
       850        860        870        880        890        900
RREHSPDSDA YNSGDDKNEK HRLLSQVVRP QESRSLSPSH LTEDRQGRWK EEDRKPERKE
       910        920        930        940        950        960
SSRRYEEQEL KEKVSSVDKQ REQTEILESS RMRAQDIIGH HQSEDRETSD RAHDENKKKA
       970        980        990       1000       1010       1020
KIQKKPIKKK KEDDVGIERG NIETTSEDGQ VFSPKKGQKK KSIEKKRKKS KGDSDISDEE
      1030       1040       1050       1060       1070       1080
AAQQSKKKRG PRTPPITTKE ELVEMCNGKN GILEDSQKKE DTAFSDWSDE DVPDRTEVTE
      1090       1100       1110       1120       1130       1140
AEHTATATTP GSTPSPLSSL LPPPPPVATA TATTVPATLA ATTAAAATSF STSAITISTS
      1150       1160       1170       1180       1190       1200
ATPTNTTNNT FANEDSHRKC HRTRVEKVET PHVTIEDAQH RKPMDQKRSS SLGSNRSNRS
      1210       1220       1230       1240       1250       1260
HTSGRLRSPS NDSAHRSGDD QSGRKRVLHS GSRDREKTKS LEITGERKSR IDQLKRGEPS
      1270       1280       1290       1300       1310       1320
RSTSSDRQDS RSHSSRRSSP ESDRQVHSRS GSFDSRDRLQ ERDRYEHDRE RERERRDTRQ
      1330       1340       1350       1360       1370       1380
REWDRDADKD WPRNRDRDRL RERERERERD KRRDLDRERE RLISDSVERD RDRDRDRTFE
      1390       1400       1410       1420       1430       1440
SSQIESVKRC EAKLEGEHER DLESTSRDSL ALDKERMDKD LGSVQGFEET NKSERTESLE
      1450       1460       1470       1480       1490       1500
GDDESKLDDA HSLGSGAGEG YEPISDDELD EILAGDAEKR EDQQDEEKMP DPLDVIDVDW
      1510       1520       1530       1540       1550       1560
SGLMPKHPKE PREPGAALLK FTPGAVMLRV GISKKLAGSE LFAKVKETCQ RLLEKPKDAD
      1570       1580       1590       1600       1610       1620
NLFEHELGAL NMAALLRKEE RASLLSNLGP CCKALCFRRD SAIRKQLVKN EKGTIKQAYT
      1630       1640       1650       1660
SAPMVDNELL RLSLRLFKRK TTCHAPGHEK TEDNKLSQSS IQQELCVS

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q5T200-1-unknown	MSKIRR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q5T200-1-unknown	MSKIRR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt95003
Q5T200-30-unknown	LGPSTG...	30	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10344
Q5T200-30-unknown	LGPSTG...	30	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137544
Q5T200-160-unknown	YVHELS...	160		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q5T200-160-unknown	YVHELS...	160	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162324
Q5T200-160-	YVHELS...	160		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q5T200-179-unknown	KLEQEN...	179	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14571
Q5T200-179-unknown	KLEQEN...	179	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt145875
Q5T200-370-unknown	SASPYP...	370		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q5T200-370-unknown	SASPYP...	370	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162322
Q5T200-370-	SASPYP...	370		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q5T200-370-	SASPYP...	370		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q5T200-875-	SLSPSH...	875		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q5T200-875-unknown	SLSPSH...	875	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177060

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SVFERL	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10344
...SVFERL	29	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120527
...QRELMK	178	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14571
...QRELMK	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129173
...ELCVS	1668	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	29	FERL.\|.LGPS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	178	ELMK.\|.KLEQ	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

TopFIND

Q5T200: Zinc finger CCCH domain-containing protein 13 {ECO:0000305}

General Information

9

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

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Protein Neighborhood

Domains & Features

9 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates