Q8WX93: Palladin

General Information

Protein names	- Palladin - SIH002 - Sarcoma antigen NY-SAR-77
Gene names	PALLD
Organism	Homo sapiens
Protease Family
Protease ID	I43.001
Chromosome location
UniProt ID	Q8WX93

8 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Palladin - Isoform 3 of Palladin - Isoform 4 of Palladin - Isoform 5 of Palladin - Isoform 6 of Palladin - Isoform 7 of Palladin - Isoform 8 of Palladin - Isoform 9 of Palladin

Sequence View

        10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL         10         20         30         40         50         60
MSGTSSHESF YDSLSDMQEE SKNTDFFPGL SAFLSQEEIN KSLDLARRAI ADSETEDFDS
        70         80         90        100        110        120
EKEISQIFST SPASLCEHPS HKETKLGEHA SRRPQDNRST PVQPLAEKQT KSISSPVSKR
       130        140        150        160        170        180
KPAMSPLLTR PSYIRSLRKA EKRGAKTPST NVKPKTPHQR KGGPQSQLCD KAANLIEELT
       190        200        210        220        230        240
SIFKAAKPRN RSPNGESSSP DSGYLSPKNQ PSALLSASAS QSPMEDQGEM EREVKSPGAR
       250        260        270        280        290        300
HCYQDNQDLA VPHNRKSHPQ PHSALHFPAA PRFIQKLRSQ EVAEGSRVYL ECRVTGNPTP
       310        320        330        340        350        360
RVRWFCEGKE LHNTPDIQIH CEGGDLHTLI IAEAFEDDTG RYTCLATNPS GSDTTSAEVF
       370        380        390        400        410        420
IEGASSTDSD SESLAFKSRA GAMPQAQKKT TSVSLTIGSS SPKTGVTTAV IQPLSVPVQQ
       430        440        450        460        470        480
VHSPTSYLCR PDGTTTAYFP PVFTKELQNT AVAEGQVVVL ECRVRGAPPL QVQWFRQGSE
       490        500        510        520        530        540
IQDSPDFRIL QKKPRSTAEP EEICTLVIAE TFPEDAGIFT CSARNDYGSA TSTAQLVVTS
       550        560        570        580        590        600
ANTENCSYES MGESNNDHFQ HFPPPPPILE TSSLELASKK PSEIQQVNNP ELGLSRAALQ
       610        620        630        640        650        660
MQFNAAERET NGVHPSRGVN GLINGKANSN KSLPTPAVLL SPTKEPPPLL AKPKLDPLKL
       670        680        690        700        710        720
QQLQNQIRLE QEAGARQPPP APRSAPPSPP FPPPPAFPEL AACTPPASPE PMSALASRSA
       730        740        750        760        770        780
PAMQSSGSFN YARPKQFIAA QNLGPASGHG TPASSPSSSS LPSPMSPTPR QFGRAPVPPF
       790        800        810        820        830        840
AQPFGAEPEA PWGSSSPSPP PPPPPVFSPT AAFPVPDVFP LPPPPPPLPS PGQASHCSSP
       850        860        870        880        890        900
ATRFGHSQTP AAFLSALLPS QPPPAAVNAL GLPKGVTPAG FPKKASRTAR IASDEEIQGT
       910        920        930        940        950        960
KDAVIQDLER KLRFKEDLLN NGQPRLTYEE RMARRLLGAD SATVFNIQEP EEETANQEYK
       970        980        990       1000       1010       1020
VSSCEQRLIS EIEYRLERSP VDESGDEVQY GDVPVENGMA PFFEMKLKHY KIFEGMPVTF
      1030       1040       1050       1060       1070       1080
TCRVAGNPKP KIYWFKDGKQ ISPKSDHYTI QRDLDGTCSL HTTASTLDDD GNYTIMAANP
      1090       1100       1110       1120       1130       1140
QGRISCTGRL MVQAVNQRGR SPRSPSGHPH VRRPRSRSRD SGDENEPIQE RFFRPHFLQA
      1150       1160       1170       1180       1190       1200
PGDLTVQEGK LCRMDCKVSG LPTPDLSWQL DGKPVRPDSA HKMLVRENGV HSLIIEPVTS
      1210       1220       1230       1240       1250       1260
RDAGIYTCIA TNRAGQNSFS LELVVAAKEA HKPPVFIEKL QNTGVADGYP VRLECRVLGV
      1270       1280       1290       1300       1310       1320
PPPQIFWKKE NESLTHSTDR VSMHQDNHGY ICLLIQGATK EDAGWYTVSA KNEAGIVSCT
      1330       1340       1350       1360       1370       1380
ARLDVYTQWH QQSQSTKPKK VRPSASRYAA LSDQGLDIKA AFQPEANPSH LTLNTALVES

EDL

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8WX93-1-unknown	MSGTSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8WX93-1-unknown	MSGTSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84184
Q8WX93-1-unknown	MSGTSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84187
Q8WX93-1-unknown	MSGTSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84188
Q8WX93-1-unknown	MSGTSS...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84191
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84185
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84190
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108024
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108025
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108026
Q8WX93-383-unknown	MPQAQK...	383	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108027
Q8WX93-669-unknown	LEQEAG...	669	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q8WX93-669-unknown	LEQEAG...	669	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt200125
Q8WX93-712-unknown	MSALAS...	712	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84186
Q8WX93-712-unknown	MSALAS...	712	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108071
Q8WX93-941-	SATVFN...	941		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q8WX93-941-unknown	SATVFN...	941	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175716
Q8WX93-941-unknown	SATVFN...	941	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175714
Q8WX93-941-unknown	SATVFN...	941	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175717
Q8WX93-941-unknown	SATVFN...	941	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175715
Q8WX93-941-unknown	SATVFN...	941	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175718
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt84189
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108214
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108212
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108215
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108213
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108216
Q8WX93-999-unknown	MAPFFE...	999	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt108211
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10446
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143573
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152155
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153586
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156192
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156859
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156860
Q8WX93-1120-unknown	DSGDEN...	1120	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt156947

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RSRSRD	1119	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10446
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126815
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135565
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137009
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139657
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140356
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140357
...RSRSRD	1119	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt140436
...ESEDL	1383	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ESEDL	1383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79807
...ESEDL	1383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79804
...ESEDL	1383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79808
...ESEDL	1383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79803
...ESEDL	1383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79805

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	1119	RSRD.\|.DSGD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)