P62899: 60S ribosomal protein L31

General Information

Protein names	- 60S ribosomal protein L31 - Large ribosomal subunit protein eL31 {ECO:0000303\|PubMed:24524803}
Gene names	RPL31
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62899

7 N-termini

2 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of 60S ribosomal protein L31 - Isoform 3 of 60S ribosomal protein L31

Sequence View

        10         20         30         40         50         60
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP
        70         80         90        100        110        120
DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN KLYTLVTYVP VTTFKNLQTV

NVDEN         10         20         30         40         50         60
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP
        70         80         90        100        110        120
DVRIDTRLNK AVWAKGIRNV PYRIRVRLSR KRNEDEDSPN KLYTLVTYVP VTTFKNLQTV

NVDEN

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62899-1-unknown	MAPAKK...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87824
P62899-1-unknown	MAPAKK...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87825
P62899-1-Acetylation	MAPAKK...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62899-1-Acetylation	MAPAKK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62899-1-Acetylation	MAPAKK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62899-1-Acetylation	MAPAKK...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104205
P62899-1-Acetylation	MAPAKK...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104206
P62899-2-unknown	APAKKG...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62899-2-unknown	APAKKG...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62899-2-unknown	APAKKG...	2		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162371
P62899-2-unknown	APAKKG...	2		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162372
P62899-4-unknown	AKKGGE...	4		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10144
P62899-4-unknown	AKKGGE...	4		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194609
P62899-4-unknown	AKKGGE...	4		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194610
P62899-15-	SAINEV...	15			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62899-15-	SAINEV...	15			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P62899-15-	SAINEV...	15			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P62899-15-unknown	SAINEV...	15		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169889
P62899-15-unknown	SAINEV...	15		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169890
P62899-45-unknown	ALKEIR...	45		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10145
P62899-45-unknown	ALKEIR...	45		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138756
P62899-45-unknown	ALKEIR...	45		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138757

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KRAPRA	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10145
...KRAPRA	44	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121811
...KRAPRA	44	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121812
...NVDEN	125	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	3	MAPA.\|.AKKG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	44	APRA.\|.ALKE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)