TopFIND 4.0

Q8IUC6: TIR domain-containing adapter molecule 1

General Information

Protein names
- TIR domain-containing adapter molecule 1
- TICAM-1
- Proline-rich, vinculin and TIR domain-containing protein B
- Putative NF-kappa-B-activating protein 502H
- Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta
- MyD88-3
- TIR domain-containing adapter protein inducing IFN-beta
Gene names TICAM1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8IUC6

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MACTGPSLPS AFDILGAAGQ DKLLYLKHKL KTPRPGCQGQ DLLHAMVLLK LGQETEARIS 
        70         80         90        100        110        120 
LEALKADAVA RLVARQWAGV DSTEDPEEPP DVSWAVARLY HLLAEEKLCP ASLRDVAYQE 
       130        140        150        160        170        180 
AVRTLSSRDD HRLGELQDEA RNRCGWDIAG DPGSIRTLQS NLGCLPPSSA LPSGTRSLPR 
       190        200        210        220        230        240 
PIDGVSDWSQ GCSLRSTGSP ASLASNLEIS QSPTMPFLSL HRSPHGPSKL CDDPQASLVP 
       250        260        270        280        290        300 
EPVPGGCQEP EEMSWPPSGE IASPPELPSS PPPGLPEVAP DATSTGLPDT PAAPETSTNY 
       310        320        330        340        350        360 
PVECTEGSAG PQSLPLPILE PVKNPCSVKD QTPLQLSVED TTSPNTKPCP PTPTTPETSP 
       370        380        390        400        410        420 
PPPPPPPSST PCSAHLTPSS LFPSSLESSS EQKFYNFVIL HARADEHIAL RVREKLEALG 
       430        440        450        460        470        480 
VPDGATFCED FQVPGRGELS CLQDAIDHSA FIILLLTSNF DCRLSLHQVN QAMMSNLTRQ 
       490        500        510        520        530        540 
GSPDCVIPFL PLESSPAQLS SDTASLLSGL VRLDEHSQIF ARKVANTFKP HRLQARKAMW 
       550        560        570        580        590        600 
RKEQDTRALR EQSQHLDGER MQAAALNAAY SAYLQSYLSY QAQMEQLQVA FGSHMSFGTG 
       610        620        630        640        650        660 
APYGARMPFG GQVPLGAPPP FPTWPGCPQP PPLHAWQAGT PPPPSPQPAA FPQSLPFPQS 
       670        680        690        700        710    
PAFPTASPAP PQSPGLQPLI IHHAQMVQLG LNNHMWNQRG SQAPEDKTQE AE

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8IUC6-1-unknown MACTGP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8IUC6-399-unknown ILHARA... 399 inferred from cleavage unknown TopFIND Inferred from cleavage TC10413

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)