TopFIND 4.0

P62888: 60S ribosomal protein L30

General Information

Protein names	- 60S ribosomal protein L30 - Large ribosomal subunit protein eL30 {ECO:0000303\|PubMed:24524803}
Gene names	RPL30
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62888

9

N-termini

6

C-termini

3

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQTLKMIRQ GKAKLVILAN NCPALRKSEI
70 80 90 100 110
EYYAMLAKTG VHHYSGNNIE LGTACGKYYR VCTLAIIDPG DSDIIRSMPE QTGEK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 6 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62888-1-acetylation	MVAAKK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62888-1-acetylation	MVAAKK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62888-1-unknown	MVAAKK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62888-2-unknown	VAAKKT...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62888-2-unknown	VAAKKT...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62888-6-unknown	KTKKSL...	6		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10143
P62888-9-	KSLESI...	9			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62888-65-unknown	MLAKTG...	65		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000430506
P62888-76-unknown	GNNIEL...	76		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6136
P62888-95-	AIIDPG...	95			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P62888-95-	AIIDPG...	95			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P62888-96-unknown	IIDPGD...	96		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7656

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MVAAKK	5	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10143
	...VHHYSG	75	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6136
	...VCTLAI	95	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC7656
	...EQTGEK	114	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000429483
	...QTGEK	115	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...QTGEK	115		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...QTGEK	115		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...QTGEK	115		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
	...QTGEK	115		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	5	AAKK.\|.KTKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATL1_HUMAN	75	HYSG.\|.GNNI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	95	TLAI.\|.IIDP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)