A5A3E0: POTE ankyrin domain family member F

General Information

Protein names	- POTE ankyrin domain family member F - ANKRD26-like family C member 1B - Chimeric POTE-actin protein
Gene names	POTEF
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	A5A3E0

11 N-termini

9 C-termini

11 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVVEVDSMPA ASSVKKPFGL RSKMGKWCCR CFPCCRESGK SNVGTSGDHD DSAMKTLRSK
        70         80         90        100        110        120
MGKWCRHCFP CCRGSGKSNV GASGDHDDSA MKTLRNKMGK WCCHCFPCCR GSSKSKVGAW
       130        140        150        160        170        180
GDYDDSAFME PRYHVRGEDL DKLHRAAWWG KVPRKDLIVM LRDTDVNKQD KQKRTALHLA
       190        200        210        220        230        240
SANGNSEVVK LLLDRRCQLN VLDNKKRTAL IKAVQCQEDE CALMLLEHGT DPNIPDEYGN
       250        260        270        280        290        300
TTLHYAIYNE DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA
       310        320        330        340        350        360
LDRYGRTALI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSHH HVICQLLSDY
       370        380        390        400        410        420
KEKQMLKISS ENSNPEQDLK LTSEEESQRF KGSENSQPEK MSQEPEINKD GDREVEEEMK
       430        440        450        460        470        480
KHESNNVGLL ENLTNGVTAG NGDNGLIPQR KSRTPENQQF PDNESEEYHR ICELLSDYKE
       490        500        510        520        530        540
KQMPKYSSEN SNPEQDLKLT SEEESQRLKG SENGQPEKRS QEPEINKDGD RELENFMAIE
       550        560        570        580        590        600
EMKKHRSTHV GFPENLTNGA TAGNGDDGLI PPRKSRTPES QQFPDTENEE YHSDEQNDTQ
       610        620        630        640        650        660
KQFCEEQNTG ILHDEILIHE EKQIEVVEKM NSELSLSCKK EKDILHENST LREEIAMLRL
       670        680        690        700        710        720
ELDTMKHQSQ LREKKYLEDI ESVKKRNDNL LKALQLNELT MDDDTAVLVI DNGSGMCKAG
       730        740        750        760        770        780
FAGDDAPRAV FPSIVGRPRQ QGMMGGMHQK ESYVGKEAQS KRGILTLKYP MEHGIITNWD
       790        800        810        820        830        840
DMEKIWHHTF YNELRVAPEE HPVLLTEATL NPKANREKMT QIMFETFNTP AMYVAIQAVL
       850        860        870        880        890        900
SLYTSGRTTG IVMDSGDGVT HTVPIYEGNA LPHATLRLDL AGRELPDYLM KILTEHGYRF
       910        920        930        940        950        960
TTMAEREIVR DIKEKLCYVA LDFEQEMATV ASSSSLEKSY ELPDGQVITI GNERFRCPEA
       970        980        990       1000       1010       1020
LFQPCFLGME SCGIHETTFN SIMKSDVDIR KDLYTNTVLS GGTTMYPGMA HRMQKEIAAL
      1030       1040       1050       1060       1070
APSMMKIRII APPKRKYSVW VGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCL

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

11 N-termini - 9 C-termini - 11 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
A5A3E0-1-unknown	MVVEVD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
A5A3E0-709-unknown	VIDNGS...	709	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13687
A5A3E0-712-unknown	NGSGMC...	712	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1376
A5A3E0-718-unknown	KAGFAG...	718	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15257
A5A3E0-719-unknown	AGFAGD...	719	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC9872
A5A3E0-720-	GFAGDD...	720		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
A5A3E0-917-unknown	CYVALD...	917	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13688
A5A3E0-942-unknown	LPDGQV...	942	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18189
A5A3E0-942-unknown	LPDGQV...	942	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16848
A5A3E0-945-unknown	GQVITI...	945	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18190
A5A3E0-945-unknown	GQVITI...	945	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC1377
A5A3E0-945-unknown	GQVITI...	945	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16849
A5A3E0-946-unknown	QVITIG...	946	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16850
A5A3E0-1048-	SLSTFQ...	1048		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTAVLV	708	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13687
...VLVIDN	711	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1376
...GSGMCK	717	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15257
...SGMCKA	718	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9872
...IKEKLC	916	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13688
...EKSYEL	941	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18189
...EKSYEL	941	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16848
...YELPDG	944	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18190
...YELPDG	944	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1377
...YELPDG	944	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16849
...ELPDGQ	945	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16850
...HRKCL	1075	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	708	AVLV.\|.VIDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP3_HUMAN	711	VIDN.\|.NGSG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
HTRA2_HUMAN	717	GMCK.\|.KAGF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	718	MCKA.\|.AGFA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	916	EKLC.\|.CYVA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
MEP1B_HUMAN	941	SYEL.\|.LPDG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	941	SYEL.\|.LPDG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	944	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP3_HUMAN	944	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
MEP1A_HUMAN	944	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	945	PDGQ.\|.QVIT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)