Q9NY65: Tubulin alpha-8 chain

General Information

Protein names	- Tubulin alpha-8 chain - Alpha-tubulin 8 - Tubulin alpha chain-like 2
Gene names	TUBA8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NY65

22 N-termini

22 C-termini

24 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRECISVHVG QAGVQIGNAC WELFCLEHGI QADGTFDAQA SKINDDDSFT TFFSETGNGK
        70         80         90        100        110        120
HVPRAVMIDL EPTVVDEVRA GTYRQLFHPE QLITGKEDAA NNYARGHYTV GKESIDLVLD
       130        140        150        160        170        180
RIRKLTDACS GLQGFLIFHS FGGGTGSGFT SLLMERLSLD YGKKSKLEFA IYPAPQVSTA
       190        200        210        220        230        240
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL ISQIVSSITA
       250        260        270        280        290        300
SLRFDGALNV DLTEFQTNLV PYPRIHFPLV TYAPIISAEK AYHEQLSVAE ITSSCFEPNS
       310        320        330        340        350        360
QMVKCDPRHG KYMACCMLYR GDVVPKDVNV AIAAIKTKRT IQFVDWCPTG FKVGINYQPP
       370        380        390        400        410        420
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE
       430        440
AREDLAALEK DYEEVGTDSF EEENEGEEF

Isoforms

- Isoform 2 of Tubulin alpha-8 chain

Sequence View

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NY65-1-unknown	MRECIS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NY65-13-unknown	GVQIGN...	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4262
Q9NY65-14-unknown	VQIGNA...	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4263
Q9NY65-67-unknown	MIDLEP...	67	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91580
Q9NY65-85-unknown	QLFHPE...	85	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10566
Q9NY65-85-unknown	QLFHPE...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt136776
Q9NY65-91-unknown	QLITGK...	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13438
Q9NY65-91-unknown	QLITGK...	91	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137197
Q9NY65-93-unknown	ITGKED...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15535
Q9NY65-93-unknown	ITGKED...	93	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt137355
Q9NY65-138-unknown	FHSFGG...	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15537
Q9NY65-138-unknown	FHSFGG...	138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140799
Q9NY65-201-unknown	AFMVDN...	201	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15539
Q9NY65-201-unknown	AFMVDN...	201	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15070
Q9NY65-201-unknown	AFMVDN...	201	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144090
Q9NY65-205-unknown	DNEAIY...	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15541
Q9NY65-205-unknown	DNEAIY...	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144266
Q9NY65-206-unknown	NEAIYD...	206	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13440
Q9NY65-206-unknown	NEAIYD...	206	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144305
Q9NY65-208-unknown	AIYDIC...	208	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13442
Q9NY65-208-unknown	AIYDIC...	208	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144408
Q9NY65-252-unknown	LTEFQT...	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13444
Q9NY65-252-unknown	LTEFQT...	252	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146106
Q9NY65-254-unknown	EFQTNL...	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15543
Q9NY65-254-unknown	EFQTNL...	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146191
Q9NY65-353-unknown	VGINYQ...	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10568
Q9NY65-353-unknown	VGINYQ...	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149510
Q9NY65-354-unknown	GINYQP...	354	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15545
Q9NY65-354-unknown	GINYQP...	354	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149550
Q9NY65-356-unknown	NYQPPT...	356	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15072
Q9NY65-356-unknown	NYQPPT...	356	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149588
Q9NY65-357-unknown	YQPPTV...	357	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6824
Q9NY65-357-unknown	YQPPTV...	357	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18145
Q9NY65-357-unknown	YQPPTV...	357	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149618
Q9NY65-358-unknown	QPPTVV...	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19819
Q9NY65-358-unknown	QPPTVV...	358	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18147
Q9NY65-358-unknown	QPPTVV...	358	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149653
Q9NY65-368-unknown	LAKVQR...	368	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13446
Q9NY65-368-unknown	LAKVQR...	368	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt149929
Q9NY65-408-unknown	YVGEGM...	408	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15547
Q9NY65-408-unknown	YVGEGM...	408	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150785
Q9NY65-414-unknown	EEGEFS...	414	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15549
Q9NY65-414-unknown	EEGEFS...	414	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150909

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HVGQAG	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4262
...VGQAGV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4263
...AGTYRQ	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10566
...LFHPEQ	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13438
...LFHPEQ	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120112
...HPEQLI	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15535
...HPEQLI	92	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120300
...QGFLIF	137	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15537
...QGFLIF	137	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123936
...EHSDCA	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15539
...EHSDCA	200	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15070
...EHSDCA	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127341
...CAFMVD	204	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15541
...CAFMVD	204	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127522
...AFMVDN	205	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13440
...AFMVDN	205	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127565
...MVDNEA	207	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13442
...MVDNEA	207	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127672
...ALNVDL	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13444
...ALNVDL	251	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129406
...NVDLTE	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15543
...NVDLTE	253	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129493
...PTGFKV	352	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10568
...PTGFKV	352	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132895
...TGFKVG	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15545
...TGFKVG	353	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132938
...FKVGIN	355	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15072
...FKVGIN	355	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132976
...KVGINY	356	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6824
...KVGINY	356	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18145
...KVGINY	356	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133005
...VGINYQ	357	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19819
...VGINYQ	357	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18147
...VGINYQ	357	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133040
...VPGGDL	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13446
...VPGGDL	367	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133320
...AFVHWY	407	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15547
...AFVHWY	407	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134187
...VGEGME	413	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15549
...VGEGME	413	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134311
...NEGEEF	448	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8293
...NEGEEF	448	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135103
...EGEEF	449	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGEEF	449	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87198

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	12	GQAG.\|.GVQI	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	13	QAGV.\|.VQIG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAA_HUMAN	84	TYRQ.\|.QLFH	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	90	HPEQ.\|.QLIT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	92	EQLI.\|.ITGK	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	137	FLIF.\|.FHSF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	200	SDCA.\|.AFMV	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	200	SDCA.\|.AFMV	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
HTRA2_HUMAN	204	FMVD.\|.DNEA	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAB_HUMAN	205	MVDN.\|.NEAI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	207	DNEA.\|.AIYD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAB_HUMAN	251	NVDL.\|.LTEF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	253	DLTE.\|.EFQT	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	352	GFKV.\|.VGIN	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
HTRA2_HUMAN	353	FKVG.\|.GINY	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	355	VGIN.\|.NYQP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATL1_HUMAN	356	GINY.\|.YQPP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	356	GINY.\|.YQPP	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	357	INYQ.\|.QPPT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	357	INYQ.\|.QPPT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	367	GGDL.\|.LAKV	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
HTRA2_HUMAN	407	VHWY.\|.YVGE	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	413	EGME.\|.EEGE	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
CBPC1_HUMAN	448	GEEF.\|.F	inferred from experiment	unknown	MEROPS		Merops CBPC1_HUMAN -> TBA8_HUMAN @448

TopFIND

Q9NY65: Tubulin alpha-8 chain

General Information

22

N-termini

22

C-termini

24

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

22 N-termini - 22 C-termini - 24 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates