Q6FIF0: AN1-type zinc finger protein 6

General Information

Protein names	- AN1-type zinc finger protein 6 - Associated with PRK1 protein - Zinc finger A20 domain-containing protein 3
Gene names	ZFAND6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6FIF0

8 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAQETNHSQV PMLCSTGCGF YGNPRTNGMC SVCYKEHLQR QNSSNGRISP PATSVSSLSE
        70         80         90        100        110        120
SLPVQCTDGS VPEAQSALDS TSSSMQPSPV SNQSLLSESV ASSQLDSTSV DKAVPETEDV
       130        140        150        160        170        180
QASVSDTAQQ PSEEQSKSLE KPKQKKNRCF MCRKKVGLTG FECRCGNVYC GVHRYSDVHN
       190        200
CSYNYKADAA EKIRKENPVV VGEKIQKI

Isoforms

- Isoform 2 of AN1-type zinc finger protein 6

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

8 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6FIF0-1-unknown	MAQETN...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6FIF0-1-unknown	MAQETN...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt95099
Q6FIF0-2-acetylation	AQETNH...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q6FIF0-2-acetylation	AQETNH...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q6FIF0-2-acetylation	AQETNH...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162401
Q6FIF0-107-unknown	STSVDK...	107		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172889
Q6FIF0-107-	STSVDK...	107			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6FIF0-107-	STSVDK...	107			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6FIF0-107-	STSVDK...	107			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q6FIF0-113-unknown	AVPETE...	113			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q6FIF0-113-unknown	AVPETE...	113		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162333
Q6FIF0-113-	AVPETE...	113			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q6FIF0-113-	AVPETE...	113			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q6FIF0-113-	AVPETE...	113			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q6FIF0-113-	AVPETE...	113			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q6FIF0-127-unknown	TAQQPS...	127		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165770
Q6FIF0-127-	TAQQPS...	127			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EKIQKI	207	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8250
...EKIQKI	207	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt129763
...KIQKI	208		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KIQKI	208	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KIQKI	208	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90717
...KIQKI	208		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA4_HUMAN	207	IQKI.\|.I	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)