P15104: Glutamine synthetase {ECO:0000303|PubMed:2888076, ECO:0000303|PubMed:30158707}

General Information

Protein names	- Glutamine synthetase {ECO:0000303\|PubMed:2888076, ECO:0000303\|PubMed:30158707} - GS {ECO:0000303\|PubMed:1681907, ECO:0000303\|PubMed:30158707} - 6.3.1.2 {ECO:0000269\|PubMed:30158707} - Glutamate--ammonia ligase {ECO:0000305} - Palmitoyltransferase GLUL {ECO:0000305} - 2.3.1.225 {ECO:0000305\|PubMed:30158707}
Gene names	GLUL
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P15104

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTTSASSHLN KGIKQVYMSL PQGEKVQAMY IWIDGTGEGL RCKTRTLDSE PKCVEELPEW
        70         80         90        100        110        120
NFDGSSTLQS EGSNSDMYLV PAAMFRDPFR KDPNKLVLCE VFKYNRRPAE TNLRHTCKRI
       130        140        150        160        170        180
MDMVSNQHPW FGMEQEYTLM GTDGHPFGWP SNGFPGPQGP YYCGVGADRA YGRDIVEAHY
       190        200        210        220        230        240
RACLYAGVKI AGTNAEVMPA QWEFQIGPCE GISMGDHLWV ARFILHRVCE DFGVIATFDP
       250        260        270        280        290        300
KPIPGNWNGA GCHTNFSTKA MREENGLKYI EEAIEKLSKR HQYHIRAYDP KGGLDNARRL
       310        320        330        340        350        360
TGFHETSNIN DFSAGVANRS ASIRIPRTVG QEKKGYFEDR RPSANCDPFS VTEALIRTCL
       370
LNETGDEPFQ YKN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P15104-2-unknown	MTTSAS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P15104-2-Acetylation	TTSASS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PFQYKN	372	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8225
...FQYKN	373	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...FQYKN	373		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FQYKN	373		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...FQYKN	373		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...FQYKN	373		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA4_HUMAN	372	QYKN.\|.N	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)