Q9UHG2: ProSAAS
Protein names | - ProSAAS - Proprotein convertase subtilisin/kexin type 1 inhibitor - Proprotein convertase 1 inhibitor - pro-SAAS - KEP - Big SAAS - b-SAAS - Little SAAS - l-SAAS - N-proSAAS - Big PEN-LEN - b-PEN-LEN - SAAS CT(1-49) - PEN - Little LEN - l-LEN - Big LEN - b-LEN - SAAS CT(25-40) |
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Gene names | PCSK1N |
Organism | Homo sapiens |
Protease Family | |
Protease ID | I49.001 |
Chromosome location | |
UniProt ID | Q9UHG2 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAGSPLLWGP RAGGVGLLVL LLLGLFRPPP ALCARPVKEP RGLSAASPPL AETGAPRRFR
70 80 90 100 110 120
RSVPRGEAAG AVQELARALA HLLEAERQER ARAEAQEAED QQARVLAQLL RVWGAPRNSD
130 140 150 160 170 180
PALGLDDDPD APAAQLARAL LRARLDPAAL AAQLVPAPVP AAALRPRPPV YDDGPAGPDA
190 200 210 220 230 240
EEAGDETPDV DPELLRYLLG RILAGSADSE GVAAPRRLRR AADHDVGSEL PPEGVLGALL
250 260
RVKRLETPAP QVPARRLLPP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UHG2-34-unknown | ARPVKE... | 34 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UHG2-59-unknown | FRRSVP... | 59 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC8254 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GAPRRF | 58 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC8254 | |||
...RLLPP | 260 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CBPA4_HUMAN | 58 | PRRF.|.FRRS | inferred from experiment | unknown | MEROPS | Fricker LD | Tanco S et al.:Characterization of the substra... (M14.017) | 20385563, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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