TopFIND 4.0

P23946: Chymase

General Information

Protein names
- Chymase
- 3.4.21.39
- Alpha-chymase
- Mast cell protease I
Gene names CMA1
Organism Homo sapiens
Protease Family S01.140
Protease ID S01.140
Chromosome location
UniProt ID P23946

3

N-termini

2

C-termini

1

Cleavages

70

Substrates

Sequence

        10         20         30         40         50         60 
MLLLPLPLLL FLLCSRAEAG EIIGGTECKP HSRPYMAYLE IVTSNGPSKF CGGFLIRRNF 
        70         80         90        100        110        120 
VLTAAHCAGR SITVTLGAHN ITEEEDTWQK LEVIKQFRHP KYNTSTLHHD IMLLKLKEKA 
       130        140        150        160        170        180 
SLTLAVGTLP FPSQFNFVPP GRMCRVAGWG RTGVLKPGSD TLQEVKLRLM DPQACSHFRD 
       190        200        210        220        230        240 
FDHNLQLCVG NPRKTKSAFK GDSGGPLLCA GVAQGIVSYG RSDAKPPAVF TRISHYRPWI 
   
NQILQAN

Isoforms

- Isoform 2 of Chymase

Sequence View

        10         20         30         40         50         60 
MLLLPLPLLL FLLCSRAEAG EIIGGTECKP HSRPYMAYLE IVTSNGPSKF CGGFLIRRNF 
        70         80         90        100        110        120 
VLTAAHCAGR SITVTLGAHN ITEEEDTWQK LEVIKQFRHP KYNTSTLHHD IMLLKLKEKA 
       130        140        150        160        170        180 
SLTLAVGTLP FPSQFNFVPP GRMCRVAGWG RTGVLKPGSD TLQEVKLRLM DPQACSHFRD 
       190        200        210        220        230        240 
FDHNLQLCVG NPRKTKSAFK GDSGGPLLCA GVAQGIVSYG RSDAKPPAVF TRISHYRPWI 
   
NQILQAN



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 70 Substrates

N-termini

C-termini

Cleavages

Substrates