P21583: Kit ligand

General Information

Protein names	- Kit ligand - Mast cell growth factor - MGF - Stem cell factor - SCF - c-Kit ligand - Soluble KIT ligand - sKITLG
Gene names	KITLG
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P21583

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Kit ligand - Isoform 3 of Kit ligand

Sequence View

        10         20         30         40         50         60
MKKTQTWILT CIYLQLLLFN PLVKTEGICR NRVTNNVKDV TKLVANLPKD YMITLKYVPG
        70         80         90        100        110        120
MDVLPSHCWI SEMVVQLSDS LTDLLDKFSN ISEGLSNYSI IDKLVNIVDD LVECVKENSS
       130        140        150        160        170        180
KDLKKSFKSP EPRLFTPEEF FRIFNRSIDA FKDFVVASET SDCVVSSTLS PEKDSRVSVT
       190        200        210        220        230        240
KPFMLPPVAA SSLRNDSSSS NRKAKNPPGD SSLHWAAMAL PALFSLIIGF AFGALYWKKR
       250        260        270
QPSLTRAVEN IQINEEDNEI SMLQEKEREF QEV         10         20         30         40         50         60
MKKTQTWILT CIYLQLLLFN PLVKTEGICR NRVTNNVKDV TKLVANLPKD YMITLKYVPG
        70         80         90        100        110        120
MDVLPSHCWI SEMVVQLSDS LTDLLDKFSN ISEGLSNYSI IDKLVNIVDD LVECVKENSS
       130        140        150        160        170        180
KDLKKSFKSP EPRLFTPEEF FRIFNRSIDA FKDFVVASET SDCVVSSTLS PEKDSRVSVT
       190        200        210        220        230        240
KPFMLPPVAA SSLRNDSSSS NRKAKNPPGD SSLHWAAMAL PALFSLIIGF AFGALYWKKR
       250        260        270
QPSLTRAVEN IQINEEDNEI SMLQEKEREF QEV

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P21583-1-unknown	MKKTQT...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89007
P21583-26-unknown	EGICRN...	26	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P21583-26-unknown	EGICRN...	26	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114053
P21583-184-unknown	MLPPVA...	184	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8427
P21583-184-unknown	MLPPVA...	184	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144703
P21583-191-unknown	SSLRND...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC158
P21583-191-unknown	SSLRND...	191	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt144994

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VTKPFM	183	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8427
...VTKPFM	183	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127971
...PPVAAS	190	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PPVAAS	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC158
...PPVAAS	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91892
...EFQEV	273	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EFQEV	273	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84626
...EFQEV	273	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84625

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CMA1_HUMAN	183	KPFM.\|.MLPP	inferred from experiment	unknown	MEROPS	Caughey GH	Raymond WW et al.:Albumin is a substrate of human... (S01.140)	12815038,
ADA19_HUMAN	190	VAAS.\|.SSLR	inferred from experiment	unknown	MEROPS	Blobel CP	Chesneau V et al.:Catalytic properties of ADAM19.... (M12.214)	12682046,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)