TopFIND 4.0

Q9H013: Disintegrin and metalloproteinase domain-containing protein 19

General Information

Protein names
- Disintegrin and metalloproteinase domain-containing protein 19
- ADAM 19
- 3.4.24.-
- Meltrin-beta
- Metalloprotease and disintegrin dendritic antigen marker
- MADDAM
Gene names ADAM19
Organism Homo sapiens
Protease Family M12.214
Protease ID M12.214
Chromosome location
UniProt ID Q9H013

5

N-termini

3

C-termini

7

Cleavages

6

Substrates

Sequence

        10         20         30         40         50         60 
MPGGAGAARL CLLAFALQPL RPRAAREPGW TRGSEEGSPK LQHELIIPQW KTSESPVREK 
        70         80         90        100        110        120 
HPLKAELRVM AEGRELILDL EKNEQLFAPS YTETHYTSSG NPQTTTRKLE DHCFYHGTVR 
       130        140        150        160        170        180 
ETELSSVTLS TCRGIRGLIT VSSNLSYVIE PLPDSKGQHL IYRSEHLKPP PGNCGFEHSK 
       190        200        210        220        230        240 
PTTRDWALQF TQQTKKRPRR MKREDLNSMK YVELYLVADY LEFQKNRRDQ DATKHKLIEI 
       250        260        270        280        290        300 
ANYVDKFYRS LNIRIALVGL EVWTHGNMCE VSENPYSTLW SFLSWRRKLL AQKYHDNAQL 
       310        320        330        340        350        360 
ITGMSFHGTT IGLAPLMAMC SVYQSGGVNM DHSENAIGVA ATMAHEMGHN FGMTHDSADC 
       370        380        390        400        410        420 
CSASAADGGC IMAAATGHPF PKVFNGCNRR ELDRYLQSGG GMCLSNMPDT RMLYGGRRCG 
       430        440        450        460        470        480 
NGYLEDGEEC DCGEEEECNN PCCNASNCTL RPGAECAHGS CCHQCKLLAP GTLCREQARQ 
       490        500        510        520        530        540 
CDLPEFCTGK SPHCPTNFYQ MDGTPCEGGQ AYCYNGMCLT YQEQCQQLWG PGARPAPDLC 
       550        560        570        580        590        600 
FEKVNVAGDT FGNCGKDMNG EHRKCNMRDA KCGKIQCQSS EARPLESNAV PIDTTIIMNG 
       610        620        630        640        650        660 
RQIQCRGTHV YRGPEEEGDM LDPGLVMTGT KCGYNHICFE GQCRNTSFFE TEGCGKKCNG 
       670        680        690        700        710        720 
HGVCNNNQNC HCLPGWAPPF CNTPGHGGSI DSGPMPPESV GPVVAGVLVA ILVLAVLMLM 
       730        740        750        760        770        780 
YYCCRQNNKL GQLKPSALPS KLRQQFSCPF RVSQNSGTGH ANPTFKLQTP QGKRKVINTP 
       790        800        810        820        830        840 
EILRKPSQPP PRPPPDYLRG GSPPAPLPAH LSRAARNSPG PGSQIERTES SRRPPPSRPI 
       850        860        870        880        890        900 
PPAPNCIVSQ DFSRPRPPQK ALPANPVPGR RSLPRPGGAS PLRPPGAGPQ QSRPLAALAP 
       910        920        930        940        950    
KVSPREALKV KAGTRGLQGG RCRVEKTKQF MLLVVWTELP EQKPRAKHSC FLVPA

Isoforms

- Isoform B of Disintegrin and metalloproteinase domain-containing protein 19

Sequence View

        10         20         30         40         50         60 
MPGGAGAARL CLLAFALQPL RPRAAREPGW TRGSEEGSPK LQHELIIPQW KTSESPVREK 
        70         80         90        100        110        120 
HPLKAELRVM AEGRELILDL EKNEQLFAPS YTETHYTSSG NPQTTTRKLE DHCFYHGTVR 
       130        140        150        160        170        180 
ETELSSVTLS TCRGIRGLIT VSSNLSYVIE PLPDSKGQHL IYRSEHLKPP PGNCGFEHSK 
       190        200        210        220        230        240 
PTTRDWALQF TQQTKKRPRR MKREDLNSMK YVELYLVADY LEFQKNRRDQ DATKHKLIEI 
       250        260        270        280        290        300 
ANYVDKFYRS LNIRIALVGL EVWTHGNMCE VSENPYSTLW SFLSWRRKLL AQKYHDNAQL 
       310        320        330        340        350        360 
ITGMSFHGTT IGLAPLMAMC SVYQSGGVNM DHSENAIGVA ATMAHEMGHN FGMTHDSADC 
       370        380        390        400        410        420 
CSASAADGGC IMAAATGHPF PKVFNGCNRR ELDRYLQSGG GMCLSNMPDT RMLYGGRRCG 
       430        440        450        460        470        480 
NGYLEDGEEC DCGEEEECNN PCCNASNCTL RPGAECAHGS CCHQCKLLAP GTLCREQARQ 
       490        500        510        520        530        540 
CDLPEFCTGK SPHCPTNFYQ MDGTPCEGGQ AYCYNGMCLT YQEQCQQLWG PGARPAPDLC 
       550        560        570        580        590        600 
FEKVNVAGDT FGNCGKDMNG EHRKCNMRDA KCGKIQCQSS EARPLESNAV PIDTTIIMNG 
       610        620        630        640        650        660 
RQIQCRGTHV YRGPEEEGDM LDPGLVMTGT KCGYNHICFE GQCRNTSFFE TEGCGKKCNG 
       670        680        690        700        710        720 
HGVCNNNQNC HCLPGWAPPF CNTPGHGGSI DSGPMPPESV GPVVAGVLVA ILVLAVLMLM 
       730        740        750        760        770        780 
YYCCRQNNKL GQLKPSALPS KLRQQFSCPF RVSQNSGTGH ANPTFKLQTP QGKRKVINTP 
       790        800        810        820        830        840 
EILRKPSQPP PRPPPDYLRG GSPPAPLPAH LSRAARNSPG PGSQIERTES SRRPPPSRPI 
       850        860        870        880        890        900 
PPAPNCIVSQ DFSRPRPPQK ALPANPVPGR RSLPRPGGAS PLRPPGAGPQ QSRPLAALAP 
       910        920        930        940        950    
KVSPREALKV KAGTRGLQGG RCRVEKTKQF MLLVVWTELP EQKPRAKHSC FLVPA



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(REFRESH)

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 7 Cleavages - 6 Substrates

N-termini

C-termini

Cleavages

Substrates