P20366: Protachykinin-1

General Information

Protein names	- Protachykinin-1 - PPT - Substance P - Neurokinin A - NKA - Neuromedin L - Substance K - Neuropeptide K - NPK - Neuropeptide gamma - C-terminal-flanking peptide
Gene names	TAC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P20366

16 N-termini

15 C-termini

43 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Alpha of Protachykinin-1 - Isoform Gamma of Protachykinin-1 - Isoform Delta of Protachykinin-1

Sequence View

        10         20         30         40         50         60
MKILVALAVF FLVSTQLFAE EIGANDDLNY WSDWYDSDQI KEELPEPFEH LLQRIARRPK
        70         80         90        100        110        120
PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS

AMQNYERRR         10         20         30         40         50         60
MKILVALAVF FLVSTQLFAE EIGANDDLNY WSDWYDSDQI KEELPEPFEH LLQRIARRPK
        70         80         90        100        110        120
PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS

AMQNYERRR         10         20         30         40         50         60
MKILVALAVF FLVSTQLFAE EIGANDDLNY WSDWYDSDQI KEELPEPFEH LLQRIARRPK
        70         80         90        100        110        120
PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS

AMQNYERRR

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Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

16 N-termini - 15 C-termini - 43 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P20366-1-unknown	MKILVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92216
P20366-1-unknown	MKILVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92217
P20366-1-unknown	MKILVA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92218
P20366-20-unknown	EEIGAN...	20	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P20366-20-unknown	EEIGAN...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112508
P20366-20-unknown	EEIGAN...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112509
P20366-20-unknown	EEIGAN...	20	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112510
P20366-58-unknown	RPKPQQ...	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16322
P20366-58-unknown	RPKPQQ...	58	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139774
P20366-59-unknown	PKPQQF...	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32157
P20366-59-unknown	PKPQQF...	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139838
P20366-60-unknown	KPQQFF...	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8464
P20366-60-unknown	KPQQFF...	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8489
P20366-60-unknown	KPQQFF...	60	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt139876
P20366-62-unknown	QQFFGL...	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31695
P20366-62-unknown	QQFFGL...	62	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27623
P20366-62-unknown	QQFFGL...	62	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140127
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17428
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26394
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23886
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26741
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8571
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15791
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19925
P20366-64-unknown	FFGLMG...	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25083
P20366-64-unknown	FFGLMG...	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140220
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17432
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27756
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4724
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26745
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8575
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15795
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31699
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8422
P20366-65-unknown	FGLMGK...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4585
P20366-65-unknown	FGLMGK...	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140272
P20366-66-unknown	GLMGKR...	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17434
P20366-66-unknown	GLMGKR...	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31701
P20366-66-unknown	GLMGKR...	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8424
P20366-66-unknown	GLMGKR...	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140339
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17436
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26398
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27758
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26747
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8577
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8589
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15797
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19929
P20366-67-unknown	LMGKRD...	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25087
P20366-67-unknown	LMGKRD...	67	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140405
P20366-69-unknown	GKRDAD...	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC739
P20366-69-unknown	GKRDAD...	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1004
P20366-69-unknown	GKRDAD...	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140591
P20366-99-unknown	KTDSFV...	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC227
P20366-99-unknown	KTDSFV...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196938
P20366-102-unknown	SFVGLM...	102	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31703
P20366-102-unknown	SFVGLM...	102	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141678
P20366-104-unknown	VGLMGK...	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4726
P20366-104-unknown	VGLMGK...	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4587
P20366-104-unknown	VGLMGK...	104	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141769
P20366-105-unknown	GLMGKR...	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31705
P20366-105-unknown	GLMGKR...	105	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141846
P20366-106-unknown	LMGKRA...	106	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15799
P20366-106-unknown	LMGKRA...	106	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141902

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QRIARR	57	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16322
...QRIARR	57	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122868
...QRIARR	57	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122871
...QRIARR	57	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122873
...RIARRP	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32157
...RIARRP	58	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122934
...RIARRP	58	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122935
...RIARRP	58	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122937
...IARRPK	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8464
...IARRPK	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8489
...IARRPK	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122977
...IARRPK	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122979
...IARRPK	59	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122981
...RRPKPQ	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31695
...RRPKPQ	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27623
...RRPKPQ	61	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123233
...RRPKPQ	61	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123234
...RRPKPQ	61	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123235
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17428
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26394
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23886
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26741
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8571
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15791
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19925
...PKPQQF	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25083
...PKPQQF	63	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123334
...PKPQQF	63	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123335
...PKPQQF	63	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123336
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17432
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27756
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4724
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26745
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8575
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15795
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31699
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8422
...KPQQFF	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4585
...KPQQFF	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123393
...KPQQFF	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153949
...KPQQFF	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153950
...PQQFFG	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17434
...PQQFFG	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31701
...PQQFFG	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8424
...PQQFFG	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123461
...PQQFFG	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153966
...PQQFFG	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153967
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17436
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26398
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27758
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26747
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8577
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8589
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15797
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19929
...QQFFGL	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25087
...QQFFGL	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123528
...QQFFGL	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153984
...QQFFGL	66	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153985
...FFGLMG	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC739
...FFGLMG	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1004
...FFGLMG	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123725
...FFGLMG	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154012
...FFGLMG	68	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154013
...SHKRHK	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC227
...RHKTDS	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31703
...KTDSFV	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4726
...KTDSFV	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4587
...TDSFVG	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31705
...DSFVGL	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15799
...YERRR	129	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87835

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
KLK4_HUMAN	57	IARR.\|.RPKP	inferred from experiment	unknown	MEROPS	Nelson PS	Matsumura M et al.:Substrates of the prostate-spec... (S01.251)	15389820,
XPP1_HUMAN	58	ARRP.\|.PKPQ	inferred from experiment	unknown	MEROPS	Mentlein R	Harbeck HT et al.:Aminopeptidase P from rat brain... (M24.009)	1645659,
DPP2_HUMAN	59	RRPK.\|.KPQQ	inferred from experiment	unknown	MEROPS		Merops DPP2_HUMAN -> TKN1_HUMAN @59
DPP4_HUMAN	59	RRPK.\|.KPQQ	inferred from experiment	unknown	MEROPS	Sedova LR	Sedo A et al.:Dipeptidyl peptidase IV activit... (S09.003)	16277701,
THOP1_HUMAN	61	PKPQ.\|.QQFF	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
PPCE_HUMAN	61	PKPQ.\|.QQFF	inferred from experiment	unknown	MEROPS	Syed SA	Makinen PL et al.:Role of the chymotrypsin-like m... (S09.001)	7543886,
MEP1A_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Bond JS	Bertenshaw GP et al.:Marked differences between meta... (M12.002)	11278902,
MMP9_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Tokes ZA	Backstrom JR et al.:The 84-kDa form of human matrix... (M10.004)	7532211,
MMP3_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS		Merops MMP3_HUMAN -> TKN1_HUMAN @63
NEP_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Turner AJ	Matsas R et al.:The metabolism of neuropeptides... (M13.001)	6149747,
ECE1_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Turner AJ	Carson JA et al.:Characterization of PgPepO, a b... (M13.002)	12193062,
KELL_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Ouimet T	Claperon A et al.:The Kell protein of the common ... (M13.090)	15769748,
MMEL1_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Ouimet T	Rose C et al.:Cell-specific activity of nepri... (M13.008)	11964170,
MMP8_HUMAN	63	PQQF.\|.FFGL	inferred from experiment	unknown	MEROPS	Tschesche H	Diekmann O et al.:Degradation of kinins, angioten... (M10.002)	7538373,
MEP1A_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Bond JS	Bertenshaw GP et al.:Marked differences between meta... (M12.002)	11278902,
PREP_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Hersh LB	Chow KM et al.:Mammalian pitrilysin: substrate... (M16.009)	19196155,
CATE_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Yonezawa S	Kageyama T et al.:Processing of the precursors to... (A01.009)	7642580,
NEP_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS		Merops NEP_HUMAN -> TKN1_HUMAN @64
ECE1_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS		Merops ECE1_HUMAN -> TKN1_HUMAN @64
KELL_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Ouimet T	Claperon A et al.:The Kell protein of the common ... (M13.090)	15769748,
THOP1_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Watanabe K	Miyake R et al.:Two thimet oligopeptidase-like ... (M03.001)	15937176,
CMA1_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Brandt E	Schiemann F et al.:Mast cells and neutrophils prot... (S01.140)	16317101,
CATD_HUMAN	64	QQFF.\|.FGLM	inferred from experiment	unknown	MEROPS	Yonezawa S	Kageyama T et al.:Processing of the precursors to... (A01.009)	7642580,
MEP1A_HUMAN	65	QFFG.\|.GLMG	inferred from experiment	unknown	MEROPS	Bond JS	Bertenshaw GP et al.:Marked differences between meta... (M12.002)	11278902,
THOP1_HUMAN	65	QFFG.\|.GLMG	inferred from experiment	unknown	MEROPS	Watanabe K	Miyake R et al.:Two thimet oligopeptidase-like ... (M03.001)	15937176,
CMA1_HUMAN	65	QFFG.\|.GLMG	inferred from experiment	unknown	MEROPS	Brandt E	Schiemann F et al.:Mast cells and neutrophils prot... (S01.140)	16317101,
MEP1A_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Bond JS	Bertenshaw GP et al.:Marked differences between meta... (M12.002)	11278902,
MMP9_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Tokes ZA	Backstrom JR et al.:The 84-kDa form of human matrix... (M10.004)	7532211,
PREP_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Hersh LB	Chow KM et al.:Mammalian pitrilysin: substrate... (M16.009)	19196155,
NEP_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Turner AJ	Matsas R et al.:The metabolism of neuropeptides... (M13.001)	6149747,
ECE1_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Turner AJ	Carson JA et al.:Characterization of PgPepO, a b... (M13.002)	12193062,
ECE2_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Devi LA	Mzhavia N et al.:Characterization of endothelin-... (M13.003)	12560336,
KELL_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Ouimet T	Claperon A et al.:The Kell protein of the common ... (M13.090)	15769748,
MMEL1_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Ouimet T	Rose C et al.:Cell-specific activity of nepri... (M13.008)	11964170,
MMP8_HUMAN	66	FFGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Tschesche H	Diekmann O et al.:Degradation of kinins, angioten... (M10.002)	7538373,
CAN1_HUMAN	68	GLMG.\|.GKRD	inferred from experiment	unknown	MEROPS	Pennington RJ	McDermott JR et al.:Specificity of neuropeptide deg... (C02.001)	2410757,
CAN2_HUMAN	68	GLMG.\|.GKRD	inferred from experiment	unknown	MEROPS	Pennington RJ	McDermott JR et al.:Specificity of neuropeptide deg... (C02.001)	2410757,
AMPB_HUMAN	98	KRHK.\|.KTDS	inferred from experiment	unknown	MEROPS		Merops AMPB_HUMAN -> TKN1_HUMAN @98
THOP1_HUMAN	101	KTDS.\|.SFVG	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
CATE_HUMAN	103	DSFV.\|.VGLM	inferred from experiment	unknown	MEROPS	Yonezawa S	Kageyama T et al.:Processing of the precursors to... (A01.009)	7642580,
CATD_HUMAN	103	DSFV.\|.VGLM	inferred from experiment	unknown	MEROPS	Yonezawa S	Kageyama T et al.:Processing of the precursors to... (A01.009)	7642580,
THOP1_HUMAN	104	SFVG.\|.GLMG	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
KELL_HUMAN	105	FVGL.\|.LMGK	inferred from experiment	unknown	MEROPS	Ouimet T	Claperon A et al.:The Kell protein of the common ... (M13.090)	15769748,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)