TopFIND 4.0

P14091: Cathepsin E

General Information

Protein names
- Cathepsin E
- 3.4.23.34
- Cathepsin E form I
- Cathepsin E form II
Gene names CTSE
Organism Homo sapiens
Protease Family A01.010
Protease ID A01.010
Chromosome location
UniProt ID P14091

3

N-termini

3

C-termini

2

Cleavages

86

Substrates

Sequence

        10         20         30         40         50         60 
MKTLLLLLLV LLELGEAQGS LHRVPLRRHP SLKKKLRARS QLSEFWKSHN LDMIQFTESC 
        70         80         90        100        110        120 
SMDQSAKEPL INYLDMEYFG TISIGSPPQN FTVIFDTGSS NLWVPSVYCT SPACKTHSRF 
       130        140        150        160        170        180 
QPSQSSTYSQ PGQSFSIQYG TGSLSGIIGA DQVSVEGLTV VGQQFGESVT EPGQTFVDAE 
       190        200        210        220        230        240 
FDGILGLGYP SLAVGGVTPV FDNMMAQNLV DLPMFSVYMS SNPEGGAGSE LIFGGYDHSH 
       250        260        270        280        290        300 
FSGSLNWVPV TKQAYWQIAL DNIQVGGTVM FCSEGCQAIV DTGTSLITGP SDKIKQLQNA 
       310        320        330        340        350        360 
IGAAPVDGEY AVECANLNVM PDVTFTINGV PYTLSPTAYT LLDFVDGMQF CSSGFQGLDI 
       370        380        390    
HPPAGPLWIL GDVFIRQFYS VFDRGNNRVG LAPAVP

Isoforms

- Isoform 1 of Cathepsin E - Isoform 2 of Cathepsin E - Isoform 3 of Cathepsin E

Sequence View

        10         20         30         40         50         60 
MKTLLLLLLV LLELGEAQGS LHRVPLRRHP SLKKKLRARS QLSEFWKSHN LDMIQFTESC 
        70         80         90        100        110        120 
SMDQSAKEPL INYLDMEYFG TISIGSPPQN FTVIFDTGSS NLWVPSVYCT SPACKTHSRF 
       130        140        150        160        170        180 
QPSQSSTYSQ PGQSFSIQYG TGSLSGIIGA DQVSVEGLTV VGQQFGESVT EPGQTFVDAE 
       190        200        210        220        230        240 
FDGILGLGYP SLAVGGVTPV FDNMMAQNLV DLPMFSVYMS SNPEGGAGSE LIFGGYDHSH 
       250        260        270        280        290        300 
FSGSLNWVPV TKQAYWQIAL DNIQVGGTVM FCSEGCQAIV DTGTSLITGP SDKIKQLQNA 
       310        320        330        340        350        360 
IGAAPVDGEY AVECANLNVM PDVTFTINGV PYTLSPTAYT LLDFVDGMQF CSSGFQGLDI 
       370        380        390    
HPPAGPLWIL GDVFIRQFYS VFDRGNNRVG LAPAVP         10         20         30         40         50         60 
MKTLLLLLLV LLELGEAQGS LHRVPLRRHP SLKKKLRARS QLSEFWKSHN LDMIQFTESC 
        70         80         90        100        110        120 
SMDQSAKEPL INYLDMEYFG TISIGSPPQN FTVIFDTGSS NLWVPSVYCT SPACKTHSRF 
       130        140        150        160        170        180 
QPSQSSTYSQ PGQSFSIQYG TGSLSGIIGA DQVSVEGLTV VGQQFGESVT EPGQTFVDAE 
       190        200        210        220        230        240 
FDGILGLGYP SLAVGGVTPV FDNMMAQNLV DLPMFSVYMS SNPEGGAGSE LIFGGYDHSH 
       250        260        270        280        290        300 
FSGSLNWVPV TKQAYWQIAL DNIQVGGTVM FCSEGCQAIV DTGTSLITGP SDKIKQLQNA 
       310        320        330        340        350        360 
IGAAPVDGEY AVECANLNVM PDVTFTINGV PYTLSPTAYT LLDFVDGMQF CSSGFQGLDI 
       370        380        390    
HPPAGPLWIL GDVFIRQFYS VFDRGNNRVG LAPAVP         10         20         30         40         50         60 
MKTLLLLLLV LLELGEAQGS LHRVPLRRHP SLKKKLRARS QLSEFWKSHN LDMIQFTESC 
        70         80         90        100        110        120 
SMDQSAKEPL INYLDMEYFG TISIGSPPQN FTVIFDTGSS NLWVPSVYCT SPACKTHSRF 
       130        140        150        160        170        180 
QPSQSSTYSQ PGQSFSIQYG TGSLSGIIGA DQVSVEGLTV VGQQFGESVT EPGQTFVDAE 
       190        200        210        220        230        240 
FDGILGLGYP SLAVGGVTPV FDNMMAQNLV DLPMFSVYMS SNPEGGAGSE LIFGGYDHSH 
       250        260        270        280        290        300 
FSGSLNWVPV TKQAYWQIAL DNIQVGGTVM FCSEGCQAIV DTGTSLITGP SDKIKQLQNA 
       310        320        330        340        350        360 
IGAAPVDGEY AVECANLNVM PDVTFTINGV PYTLSPTAYT LLDFVDGMQF CSSGFQGLDI 
       370        380        390    
HPPAGPLWIL GDVFIRQFYS VFDRGNNRVG LAPAVP



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 86 Substrates

N-termini

C-termini

Cleavages

Substrates