P08217: Chymotrypsin-like elastase family member 2A
| Protein names | - Chymotrypsin-like elastase family member 2A - 3.4.21.71 - Elastase-2A |
|---|---|
| Gene names | CELA2A |
| Organism | Homo sapiens |
| Protease Family | S01.155 |
| Protease ID | S01.155 |
| Chromosome location | |
| UniProt ID | P08217 |
1
N-termini
2
C-termini
1
Cleavages
1
Substrates
Sequence
10 20 30 40 50 60
MIRTLLLSTL VAGALSCGDP TYPPYVTRVV GGEEARPNSW PWQVSLQYSS NGKWYHTCGG
70 80 90 100 110 120
SLIANSWVLT AAHCISSSRT YRVGLGRHNL YVAESGSLAV SVSKIVVHKD WNSNQISKGN
130 140 150 160 170 180
DIALLKLANP VSLTDKIQLA CLPPAGTILP NNYPCYVTGW GRLQTNGAVP DVLQQGRLLV
190 200 210 220 230 240
VDYATCSSSA WWGSSVKTSM ICAGGDGVIS SCNGDSGGPL NCQASDGRWQ VHGIVSFGSR
250 260
LGCNYYHKPS VFTRVSNYID WINSVIANN
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 2 C-termini - 1 Cleavages - 1 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P08217-29-unknown | VVGGEE... | 29 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P08217-29-unknown | VVGGEE... | 29 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16295 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...PYVTRV | 28 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16295 | |||
| ...VIANN | 269 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| KLK4_HUMAN | 28 | VTRV.|.VVGG | inferred from experiment | unknown | MEROPS | Nelson PS | Matsumura M et al.:Substrates of the prostate-spec... (S01.251) | 15389820, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ANGT_HUMAN | 41 | HPFH.|.HLVI | inferred from experiment | unknown | MEROPS | Salgado MC | Becari C et al.:Role of elastase-2 as an angiot... (S01.155) | 16160604, |