Q07075: Glutamyl aminopeptidase
Protein names | - Glutamyl aminopeptidase - EAP - 3.4.11.7 {ECO:0000269|PubMed:10692253, ECO:0000269|PubMed:23888046} - Aminopeptidase A - AP-A - Differentiation antigen gp160 - CD249 |
---|---|
Gene names | ENPEP |
Organism | Homo sapiens |
Protease Family | M01.003 |
Protease ID | M01.003 |
Chromosome location | |
UniProt ID | Q07075 |
1
N-termini
1
C-termini
0
Cleavages
15
Substrates
Sequence
10 20 30 40 50 60
MNFAEREGSK RYCIQTKHVA ILCAVVVGVG LIVGLAVGLT RSCDSSGDGG PGTAPAPSHL
70 80 90 100 110 120
PSSTASPSGP PAQDQDICPA SEDESGQWKN FRLPDFVNPV HYDLHVKPLL EEDTYTGTVS
130 140 150 160 170 180
ISINLSAPTR YLWLHLRETR ITRLPELKRP SGDQVQVRRC FEYKKQEYVV VEAEEELTPS
190 200 210 220 230 240
SGDGLYLLTM EFAGWLNGSL VGFYRTTYTE NGQVKSIVAT DHEPTDARKS FPCFDEPNKK
250 260 270 280 290 300
ATYTISITHP KEYGALSNMP VAKEESVDDK WTRTTFEKSV PMSTYLVCFA VHQFDSVKRI
310 320 330 340 350 360
SNSGKPLTIY VQPEQKHTAE YAANITKSVF DYFEEYFAMN YSLPKLDKIA IPDFGTGAME
370 380 390 400 410 420
NWGLITYRET NLLYDPKESA SSNQQRVATV VAHELVHQWF GNIVTMDWWE DLWLNEGFAS
430 440 450 460 470 480
FFEFLGVNHA ETDWQMRDQM LLEDVLPVQE DDSLMSSHPI IVTVTTPDEI TSVFDGISYS
490 500 510 520 530 540
KGSSILRMLE DWIKPENFQK GCQMYLEKYQ FKNAKTSDFW AALEEASRLP VKEVMDTWTR
550 560 570 580 590 600
QMGYPVLNVN GVKNITQKRF LLDPRANPSQ PPSDLGYTWN IPVKWTEDNI TSSVLFNRSE
610 620 630 640 650 660
KEGITLNSSN PSGNAFLKIN PDHIGFYRVN YEVATWDSIA TALSLNHKTF SSADRASLID
670 680 690 700 710 720
DAFALARAQL LDYKVALNLT KYLKREENFL PWQRVISAVT YIISMFEDDK ELYPMIEEYF
730 740 750 760 770 780
QGQVKPIADS LGWNDAGDHV TKLLRSSVLG FACKMGDREA LNNASSLFEQ WLNGTVSLPV
790 800 810 820 830 840
NLRLLVYRYG MQNSGNEISW NYTLEQYQKT SLAQEKEKLL YGLASVKNVT LLSRYLDLLK
850 860 870 880 890 900
DTNLIKTQDV FTVIRYISYN SYGKNMAWNW IQLNWDYLVN RYTLNNRNLG RIVTIAEPFN
910 920 930 940 950
TELQLWQMES FFAKYPQAGA GEKPREQVLE TVKNNIEWLK QHRNTIREWF FNLLESG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 15 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q07075-1-unknown | MNFAER... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LLESG | 957 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
ANGT_HUMAN | 34 | AGDR.|.RVYI | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Asparatic acid 221 is critical ... (M01.003) | 17932029, |
ANGT_HUMAN | 35 | GDRV.|.VYIH | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Asparatic acid 221 is critical ... (M01.003) | 17932029, |
TKNK-Isoform2_HUMAN | 81 | KRDM.|.MHDF | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC241 | ||
TKNK_HUMAN | 81 | KRDM.|.MHDF | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Asparatic acid 221 is critical ... (M01.003) | 17932029, |
TKNK-Isoform2_HUMAN | 82 | RDMH.|.HDFF | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC243 | ||
TKNK_HUMAN | 82 | RDMH.|.HDFF | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Asparatic acid 221 is critical ... (M01.003) | 17932029, |
CCKN_HUMAN | 96 | DRDY.|.YMGW | inferred from experiment | unknown | MEROPS | Roques BP | Migaud M et al.:The in vivo metabolism of chole... (M01.003) | 8804068, |
CMGA_HUMAN | 304 | QKEE.|.EEEE | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Enzymatic properties of human a... (M01.003) | 16790432, |
CMGA_HUMAN | 305 | KEEE.|.EEEM | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Enzymatic properties of human a... (M01.003) | 16790432, |
CMGA_HUMAN | 306 | EEEE.|.EEMA | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Enzymatic properties of human a... (M01.003) | 16790432, |
CMGA_HUMAN | 307 | EEEE.|.EMAV | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Enzymatic properties of human a... (M01.003) | 16790432, |
CMGA_HUMAN | 308 | EEEM.|.MAVV | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Enzymatic properties of human a... (M01.003) | 16790432, |
KNG1-Isoform3_HUMAN | 344 | LMKR.|.RPPG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC232 | ||
KNG1_HUMAN | 380 | LMKR.|.RPPG | inferred from experiment | unknown | MEROPS | Tsujimoto M | Goto Y et al.:Asparatic acid 221 is critical ... (M01.003) | 17932029, |
KNG1-Isoform2_HUMAN | 380 | LMKR.|.RPPG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC232 |