Q9UHF0: Tachykinin-3

General Information

Protein names	- Tachykinin-3 - ZNEUROK1 - Neurokinin-B - NKB - Neuromedin-K
Gene names	TAC3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHF0

5 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRIMLLFTAI LAFSLAQSFG AVCKEPQEEV VPGGGRSKRD PDLYQLLQRL FKSHSSLEGL
        70         80         90        100        110        120
LKALSQASTD PKESTSPEKR DMHDFFVGLM GKRSVQPDSP TDVNQENVPS FGILKYPPRA

E

Isoforms

- Isoform 2 of Tachykinin-3 - Isoform 3 of Tachykinin-3

Sequence View

        10         20         30         40         50         60
MRIMLLFTAI LAFSLAQSFG AVCKEPQEEV VPGGGRSKRD PDLYQLLQRL FKSHSSLEGL
        70         80         90        100        110        120
LKALSQASTD PKESTSPEKR DMHDFFVGLM GKRSVQPDSP TDVNQENVPS FGILKYPPRA

E         10         20         30         40         50         60
MRIMLLFTAI LAFSLAQSFG AVCKEPQEEV VPGGGRSKRD PDLYQLLQRL FKSHSSLEGL
        70         80         90        100        110        120
LKALSQASTD PKESTSPEKR DMHDFFVGLM GKRSVQPDSP TDVNQENVPS FGILKYPPRA

E

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
Q9UHF0-1-unknown	MRIMLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92224
Q9UHF0-1-unknown	MRIMLL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92225
Q9UHF0-17-unknown	QSFGAV...	17	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UHF0-17-unknown	QSFGAV...	17	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111902
Q9UHF0-17-unknown	QSFGAV...	17	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111903
Q9UHF0-21-unknown	AVCKEP...	21		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q9UHF0-21-unknown	AVCKEP...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt180667
Q9UHF0-21-unknown	AVCKEP...	21	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt180668
Q9UHF0-82-unknown	MHDFFV...	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC241
Q9UHF0-83-unknown	HDFFVG...	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC243

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PEKRDM	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC241
...PEKRDM	81	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124621
...EKRDMH	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC243
...EKRDMH	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124672
...PPRAE	121	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87843

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
AMPE_HUMAN	81	KRDM.\|.MHDF	inferred from experiment	unknown	MEROPS	Tsujimoto M	Goto Y et al.:Asparatic acid 221 is critical ... (M01.003)	17932029,
AMPE_HUMAN	82	RDMH.\|.HDFF	inferred from experiment	unknown	MEROPS	Tsujimoto M	Goto Y et al.:Asparatic acid 221 is critical ... (M01.003)	17932029,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)