TopFIND 4.0

Q8N4T0: Carboxypeptidase A6

General Information

Protein names
- Carboxypeptidase A6
- 3.4.17.-

Gene names CPA6
Organism Homo sapiens
Protease Family M14.018
Protease ID M14.018
Chromosome location
UniProt ID Q8N4T0

4

N-termini

1

C-termini

0

Cleavages

13

Substrates

Sequence

        10         20         30         40         50         60 
MKCLGKRRGQ AAAFLPLCWL FLKILQPGHS HLYNNRYAGD KVIRFIPKTE EEAYALKKIS 
        70         80         90        100        110        120 
YQLKVDLWQP SSISYVSEGT VTDVHIPQNG SRALLAFLQE ANIQYKVLIE DLQKTLEKGS 
       130        140        150        160        170        180 
SLHTQRNRRS LSGYNYEVYH SLEEIQNWMH HLNKTHSGLI HMFSIGRSYE GRSLFILKLG 
       190        200        210        220        230        240 
RRSRLKRAVW IDCGIHAREW IGPAFCQWFV KEALLTYKSD PAMRKMLNHL YFYIMPVFNV 
       250        260        270        280        290        300 
DGYHFSWTND RFWRKTRSRN SRFRCRGVDA NRNWKVKWCD EGASMHPCDD TYCGPFPESE 
       310        320        330        340        350        360 
PEVKAVANFL RKHRKHIRAY LSFHAYAQML LYPYSYKYAT IPNFRCVESA AYKAVNALQS 
       370        380        390        400        410        420 
VYGVRYRYGP ASTTLYVSSG SSMDWAYKNG IPYAFAFELR DTGYFGFLLP EMLIKPTCTE 
       430    
TMLAVKNITM HLLKKCP

Isoforms

- Isoform 2 of Carboxypeptidase A6 - Isoform 3 of Carboxypeptidase A6 - Isoform 3 of Carboxypeptidase A6

Sequence View

        10         20         30         40         50         60 
MKCLGKRRGQ AAAFLPLCWL FLKILQPGHS HLYNNRYAGD KVIRFIPKTE EEAYALKKIS 
        70         80         90        100        110        120 
YQLKVDLWQP SSISYVSEGT VTDVHIPQNG SRALLAFLQE ANIQYKVLIE DLQKTLEKGS 
       130        140        150        160        170        180 
SLHTQRNRRS LSGYNYEVYH SLEEIQNWMH HLNKTHSGLI HMFSIGRSYE GRSLFILKLG 
       190        200        210        220        230        240 
RRSRLKRAVW IDCGIHAREW IGPAFCQWFV KEALLTYKSD PAMRKMLNHL YFYIMPVFNV 
       250        260        270        280        290        300 
DGYHFSWTND RFWRKTRSRN SRFRCRGVDA NRNWKVKWCD EGASMHPCDD TYCGPFPESE 
       310        320        330        340        350        360 
PEVKAVANFL RKHRKHIRAY LSFHAYAQML LYPYSYKYAT IPNFRCVESA AYKAVNALQS 
       370        380        390        400        410        420 
VYGVRYRYGP ASTTLYVSSG SSMDWAYKNG IPYAFAFELR DTGYFGFLLP EMLIKPTCTE 
       430    
TMLAVKNITM HLLKKCP         10         20         30         40         50         60 
MKCLGKRRGQ AAAFLPLCWL FLKILQPGHS HLYNNRYAGD KVIRFIPKTE EEAYALKKIS 
        70         80         90        100        110        120 
YQLKVDLWQP SSISYVSEGT VTDVHIPQNG SRALLAFLQE ANIQYKVLIE DLQKTLEKGS 
       130        140        150        160        170        180 
SLHTQRNRRS LSGYNYEVYH SLEEIQNWMH HLNKTHSGLI HMFSIGRSYE GRSLFILKLG 
       190        200        210        220        230        240 
RRSRLKRAVW IDCGIHAREW IGPAFCQWFV KEALLTYKSD PAMRKMLNHL YFYIMPVFNV 
       250        260        270        280        290        300 
DGYHFSWTND RFWRKTRSRN SRFRCRGVDA NRNWKVKWCD EGASMHPCDD TYCGPFPESE 
       310        320        330        340        350        360 
PEVKAVANFL RKHRKHIRAY LSFHAYAQML LYPYSYKYAT IPNFRCVESA AYKAVNALQS 
       370        380        390        400        410        420 
VYGVRYRYGP ASTTLYVSSG SSMDWAYKNG IPYAFAFELR DTGYFGFLLP EMLIKPTCTE 
       430    
TMLAVKNITM HLLKKCP         10         20         30         40         50         60 
MKCLGKRRGQ AAAFLPLCWL FLKILQPGHS HLYNNRYAGD KVIRFIPKTE EEAYALKKIS 
        70         80         90        100        110        120 
YQLKVDLWQP SSISYVSEGT VTDVHIPQNG SRALLAFLQE ANIQYKVLIE DLQKTLEKGS 
       130        140        150        160        170        180 
SLHTQRNRRS LSGYNYEVYH SLEEIQNWMH HLNKTHSGLI HMFSIGRSYE GRSLFILKLG 
       190        200        210        220        230        240 
RRSRLKRAVW IDCGIHAREW IGPAFCQWFV KEALLTYKSD PAMRKMLNHL YFYIMPVFNV 
       250        260        270        280        290        300 
DGYHFSWTND RFWRKTRSRN SRFRCRGVDA NRNWKVKWCD EGASMHPCDD TYCGPFPESE 
       310        320        330        340        350        360 
PEVKAVANFL RKHRKHIRAY LSFHAYAQML LYPYSYKYAT IPNFRCVESA AYKAVNALQS 
       370        380        390        400        410        420 
VYGVRYRYGP ASTTLYVSSG SSMDWAYKNG IPYAFAFELR DTGYFGFLLP EMLIKPTCTE 
       430    
TMLAVKNITM HLLKKCP



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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 13 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKKCP 437 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LKKCP 437 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65048

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates