Q99616: C-C motif chemokine 13

General Information

Protein names	- C-C motif chemokine 13 - CK-beta-10 - Monocyte chemoattractant protein 4 - Monocyte chemotactic protein 4 - MCP-4 - NCC-1 - Small-inducible cytokine A13 - C-C motif chemokine 13, long chain - C-C motif chemokine 13, medium chain - C-C motif chemokine 13, short chain
Gene names	CCL13
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99616

11 N-termini

7 C-termini

28 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MKVSAVLLCL LLMTAAFNPQ GLAQPDALNV PSTCCFTFSS KKISLQRLKS YVITTSRCPQ
70 80 90
KAVIFRTKLG KEICADPKEK WVQNYMKHLG RKAHTLKT

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 7 C-termini - 28 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q99616-4-unknown	SAVLLC...	4		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34909
Q99616-4-unknown	SAVLLC...	4		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34948
Q99616-4-unknown	SAVLLC...	4		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34986
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34842
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34870
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34889
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34931
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34949
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34985
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35008
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35023
Q99616-5-unknown	AVLLCL...	5		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35044
Q99616-10-unknown	LLLMTA...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34929
Q99616-10-unknown	LLLMTA...	10		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34983
Q99616-17-unknown	FNPQGL...	17		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99616-22-unknown	LAQPDA...	22		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99616-24-Pyrrolidone carboxylic acid	QPDALN...	24	pyrrolidone carboxylic acid-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99616-27-unknown	ALNVPS...	27		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21796
Q99616-27-unknown	ALNVPS...	27		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23947
Q99616-28-unknown	LNVPST...	28		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21797
Q99616-28-unknown	LNVPST...	28		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23948
Q99616-31-unknown	PSTCCF...	31		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21798
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34843
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34871
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34890
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34987
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35009
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35024
Q99616-73-unknown	ICADPK...	73		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35043
Q99616-75-unknown	ADPKEK...	75		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34930
Q99616-75-unknown	ADPKEK...	75		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34984

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AVLLCL	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34929
...AVLLCL	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34983
...LAQPDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21796
...LAQPDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23947
...AQPDAL	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21797
...AQPDAL	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23948
...DALNVP	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21798
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34843
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34871
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34890
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34987
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35009
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35024
...KLGKEI	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35043
...GKEICA	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34930
...GKEICA	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34984
...HTLKT	98	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP14_HUMAN	3	MKVS.\|.SAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	3	MKVS.\|.SAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	3	MKVS.\|.SAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP1_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP12_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP13_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP8_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP9_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP25_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP2_HUMAN	9	LLCL.\|.LLLM		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	9	LLCL.\|.LLLM		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP1_HUMAN	26	QPDA.\|.ALNV	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP3_HUMAN	26	QPDA.\|.ALNV	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP1_HUMAN	27	PDAL.\|.LNVP	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP3_HUMAN	27	PDAL.\|.LNVP	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP1_HUMAN	30	LNVP.\|.PSTC	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP1_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP12_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP13_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP8_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP9_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP25_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP2_HUMAN	74	EICA.\|.ADPK		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	74	EICA.\|.ADPK		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)