P45452: Collagenase 3
Protein names | - Collagenase 3 - 3.4.24.- - Matrix metalloproteinase-13 - MMP-13 |
---|---|
Gene names | MMP13 |
Organism | Homo sapiens |
Protease Family | M10.013 |
Protease ID | M10.013 |
Chromosome location | |
UniProt ID | P45452 |
8
N-termini
9
C-termini
12
Cleavages
162
Substrates
Sequence
10 20 30 40 50 60
MHPGVLAAFL FLSWTHCRAL PLPSGGDEDD LSEEDLQFAE RYLRSYYHPT NLAGILKENA
70 80 90 100 110 120
ASSMTERLRE MQSFFGLEVT GKLDDNTLDV MKKPRCGVPD VGEYNVFPRT LKWSKMNLTY
130 140 150 160 170 180
RIVNYTPDMT HSEVEKAFKK AFKVWSDVTP LNFTRLHDGI ADIMISFGIK EHGDFYPFDG
190 200 210 220 230 240
PSGLLAHAFP PGPNYGGDAH FDDDETWTSS SKGYNLFLVA AHEFGHSLGL DHSKDPGALM
250 260 270 280 290 300
FPIYTYTGKS HFMLPDDDVQ GIQSLYGPGD EDPNPKHPKT PDKCDPSLSL DAITSLRGET
310 320 330 340 350 360
MIFKDRFFWR LHPQQVDAEL FLTKSFWPEL PNRIDAAYEH PSHDLIFIFR GRKFWALNGY
370 380 390 400 410 420
DILEGYPKKI SELGLPKEVK KISAAVHFED TGKTLLFSGN QVWRYDDTNH IMDKDYPRLI
430 440 450 460 470
EEDFPGIGDK VDAVYEKNGY IYFFNGPIQF EYSIWSNRIV RVMPANSILW C
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
8 N-termini - 9 C-termini - 12 Cleavages - 162 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P45452-55-unknown | ILKENA... | 55 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21603 | |||
P45452-58-unknown | ENAASS... | 58 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27587 | |||
P45452-77-unknown | LEVTGK... | 77 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23935 | |||
P45452-85-unknown | DNTLDV... | 85 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19109 | |||
P45452-85-unknown | DNTLDV... | 85 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17651 | |||
P45452-96-unknown | CGVPDV... | 96 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27588 | |||
P45452-104-unknown | YNVFPR... | 104 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P45452-104-unknown | YNVFPR... | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21604 | |||
P45452-104-unknown | YNVFPR... | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23936 | |||
P45452-104-unknown | YNVFPR... | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27589 | |||
P45452-104-unknown | YNVFPR... | 104 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23025 | |||
P45452-184-unknown | LLAHAF... | 184 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21416 | |||
P45452-265-unknown | LYGPGD... | 265 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21417 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...TNLAGI | 54 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21603 | |||
...AGILKE | 57 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27587 | |||
...QSFFGL | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23935 | |||
...TGKLDD | 84 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19109 | |||
...TGKLDD | 84 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17651 | |||
...MKKPRC | 95 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27588 | |||
...PDVGEY | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21604 | |||
...PDVGEY | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23936 | |||
...PDVGEY | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC27589 | |||
...PDVGEY | 103 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23025 | |||
...DGPSGL | 183 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21416 | |||
...QGIQSL | 264 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21417 | |||
...SILWC | 471 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |