TopFIND 4.0

P13501: C-C motif chemokine 5

General Information

Protein names	- C-C motif chemokine 5 - EoCP - Eosinophil chemotactic cytokine - SIS-delta - Small-inducible cytokine A5 - T cell-specific protein P228 - TCP228 - T-cell-specific protein RANTES - RANTES(3-68) - RANTES(4-68)
Gene names	CCL5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P13501

5

N-termini

3

C-termini

3

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MKVSAAALAV ILIATALCAP ASASPYSSDT TPCCFAYIAR PLPRAHIKEY FYTSGKCSNP
70 80 90
AVVFVTRKNR QVCANPEKKW VREYINSLEM S

Isoforms

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P13501-5-unknown	AAALAV...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34876
P13501-24-unknown	SPYSSD...	24		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P13501-26-unknown	YSSDTT...	26		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P13501-26-unknown	YSSDTT...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8486
P13501-27-unknown	SSDTTP...	27		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P13501-66-unknown	TRKNRQ...	66		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34955

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ASASPY	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8486
	...AVVFVT	65	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34955
	...SLEMS	91	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP13_HUMAN	4	KVSA.\|.AAAL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
DPP4_HUMAN	25	ASPY.\|.YSSD	inferred from experiment	unknown	MEROPS	De Meester I	Lambeir AM et al.:Kinetic investigation of chemok... (S09.003)	11390394,
MMP7_HUMAN	65	VFVT.\|.TRKN		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)