P02671: Fibrinogen alpha chain

General Information

Protein names	- Fibrinogen alpha chain - Fibrinopeptide A - Fibrinogen alpha chain
Gene names	FGA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02671

51 N-termini

22 C-termini

40 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFSMRIVCLV LSVVGTAWTA DSGEGDFLAE GGGVRGPRVV ERHQSACKDS DWPFCSDEDW
        70         80         90        100        110        120
NYKCPSGCRM KGLIDEVNQD FTNRINKLKN SLFEYQKNNK DSHSLTTNIM EILRGDFSSA
       130        140        150        160        170        180
NNRDNTYNRV SEDLRSRIEV LKRKVIEKVQ HIQLLQKNVR AQLVDMKRLE VDIDIKIRSC
       190        200        210        220        230        240
RGSCSRALAR EVDLKDYEDQ QKQLEQVIAK DLLPSRDRQH LPLIKMKPVP DLVPGNFKSQ
       250        260        270        280        290        300
LQKVPPEWKA LTDMPQMRME LERPGGNEIT RGGSTSYGTG SETESPRNPS SAGSWNSGSS
       310        320        330        340        350        360
GPGSTGNRNP GSSGTGGTAT WKPGSSGPGS TGSWNSGSSG TGSTGNQNPG SPRPGSTGTW
       370        380        390        400        410        420
NPGSSERGSA GHWTSESSVS GSTGQWHSES GSFRPDSPGS GNARPNNPDW GTFEEVSGNV
       430        440        450        460        470        480
SPGTRREYHT EKLVTSKGDK ELRTGKEKVT SGSTTTTRRS CSKTVTKTVI GPDGHKEVTK
       490        500        510        520        530        540
EVVTSEDGSD CPEAMDLGTL SGIGTLDGFR HRHPDEAAFF DTASTGKTFP GFFSPMLGEF
       550        560        570        580        590        600
VSETESRGSE SGIFTNTKES SSHHPGIAEF PSRGKSSSYS KQFTSSTSYN RGDSTFESKS
       610        620        630        640        650        660
YKMADEAGSE ADHEGTHSTK RGHAKSRPVR DCDDVLQTHP SGTQSGIFNI KLPGSSKIFS
       670        680        690        700        710        720
VYCDQETSLG GWLLIQQRMD GSLNFNRTWQ DYKRGFGSLN DEGEGEFWLG NDYLHLLTQR
       730        740        750        760        770        780
GSVLRVELED WAGNEAYAEY HFRVGSEAEG YALQVSSYEG TAGDALIEGS VEEGAEYTSH
       790        800        810        820        830        840
NNMQFSTFDR DADQWEENCA EVYGGGWWYN NCQAANLNGI YYPGGSYDPR NNSPYEIENG
       850        860
VVWVSFRGAD YSLRAVRMKI RPLVTQ

Isoforms

- Isoform 2 of Fibrinogen alpha chain

Sequence View

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Protein Neighborhood

Domains & Features

51 N-termini - 22 C-termini - 40 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P02671-1-unknown	MFSMRI...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75187
P02671-20-	ADSGEG...	20		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P02671-20-	ADSGEG...	20		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P02671-20-unknown	ADSGEG...	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24849
P02671-20-unknown	ADSGEG...	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC20034
P02671-20-unknown	ADSGEG...	20	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21367
P02671-20-unknown	ADSGEG...	20		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-20-unknown	ADSGEG...	20	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136823
P02671-21-unknown	DSGEGD...	21		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-21-unknown	DSGEGD...	21	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180341
P02671-22-unknown	SGEGDF...	22		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-22-unknown	SGEGDF...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180343
P02671-23-unknown	GEGDFL...	23		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-23-unknown	GEGDFL...	23	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180345
P02671-25-unknown	GDFLAE...	25		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-25-unknown	GDFLAE...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180347
P02671-26-unknown	DFLAEG...	26		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-26-unknown	DFLAEG...	26	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180349
P02671-27-unknown	FLAEGG...	27		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-27-unknown	FLAEGG...	27	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180351
P02671-28-unknown	LAEGGG...	28	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23977
P02671-28-unknown	LAEGGG...	28	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt137421
P02671-36-unknown	GPRVVE...	36	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02671-36-unknown	GPRVVE...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC27454
P02671-36-unknown	GPRVVE...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23713
P02671-36-unknown	GPRVVE...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23979
P02671-36-unknown	GPRVVE...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21456
P02671-36-unknown	GPRVVE...	36	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31739
P02671-36-unknown	GPRVVE...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115303
P02671-39-unknown	VVERHQ...	39	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15920
P02671-39-unknown	VVERHQ...	39	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC27456
P02671-39-unknown	VVERHQ...	39	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23715
P02671-39-unknown	VVERHQ...	39	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23981
P02671-39-unknown	VVERHQ...	39	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138237
P02671-105-unknown	LTTNIM...	105	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21458
P02671-105-unknown	LTTNIM...	105	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142656
P02671-117-unknown	FSSANN...	117	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23983
P02671-117-unknown	FSSANN...	117	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21460
P02671-117-unknown	FSSANN...	117	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143334
P02671-122-unknown	NRDNTY...	122	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23717
P02671-122-unknown	NRDNTY...	122	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21462
P02671-122-unknown	NRDNTY...	122	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143569
P02671-124-unknown	DNTYNR...	124	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC27458
P02671-124-unknown	DNTYNR...	124	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143649
P02671-239-unknown	SQLQKV...	239	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4350
P02671-239-unknown	SQLQKV...	239	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148051
P02671-250-unknown	ALTDMP...	250		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-250-unknown	ALTDMP...	250	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180353
P02671-259-unknown	MELERP...	259		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-259-unknown	MELERP...	259	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180355
P02671-261-unknown	LERPGG...	261	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23985
P02671-261-unknown	LERPGG...	261	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt148866
P02671-269-unknown	ITRGGS...	269	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23987
P02671-269-unknown	ITRGGS...	269	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt149103
P02671-272-unknown	GGSTSY...	272		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-272-unknown	GGSTSY...	272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180357
P02671-274-unknown	STSYGT...	274		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-274-unknown	STSYGT...	274	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180359
P02671-278-unknown	GTGSET...	278		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-278-unknown	GTGSET...	278	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180361
P02671-281-unknown	SETESP...	281		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-281-unknown	SETESP...	281	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180363
P02671-294-unknown	SWNSGS...	294		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-294-unknown	SWNSGS...	294	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180365
P02671-299-unknown	SSGPGS...	299		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-299-unknown	SSGPGS...	299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180367
P02671-355-unknown	GSTGTW...	355		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-355-unknown	GSTGTW...	355	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180369
P02671-368-unknown	GSAGHW...	368	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16421
P02671-368-unknown	GSAGHW...	368	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151364
P02671-414-unknown	EEVSGN...	414	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4352
P02671-414-unknown	EEVSGN...	414	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152218
P02671-416-unknown	VSGNVS...	416		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-416-unknown	VSGNVS...	416	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180371
P02671-427-unknown	EYHTEK...	427	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16423
P02671-427-unknown	EYHTEK...	427	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152433
P02671-433-unknown	LVTSKG...	433	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC20036
P02671-433-unknown	LVTSKG...	433	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21878
P02671-433-unknown	LVTSKG...	433	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23719
P02671-433-unknown	LVTSKG...	433	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21464
P02671-433-unknown	LVTSKG...	433		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-433-unknown	LVTSKG...	433	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152519
P02671-442-unknown	LRTGKE...	442	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24851
P02671-442-unknown	LRTGKE...	442	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21880
P02671-442-unknown	LRTGKE...	442	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21369
P02671-442-unknown	LRTGKE...	442	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23989
P02671-442-unknown	LRTGKE...	442	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152659
P02671-447-unknown	EKVTSG...	447		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-447-unknown	EKVTSG...	447	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180373
P02671-449-unknown	VTSGST...	449		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-449-unknown	VTSGST...	449	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180375
P02671-450-unknown	TSGSTT...	450		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-450-unknown	TSGSTT...	450	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180377
P02671-451-unknown	SGSTTT...	451		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-451-unknown	SGSTTT...	451	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180379
P02671-511-unknown	HRHPDE...	511	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC15922
P02671-511-unknown	HRHPDE...	511	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153542
P02671-536-unknown	MLGEFV...	536		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-536-unknown	MLGEFV...	536	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180381
P02671-538-unknown	GEFVSE...	538		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-538-unknown	GEFVSE...	538	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180383
P02671-539-unknown	EFVSET...	539		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-539-unknown	EFVSET...	539	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180385
P02671-540-unknown	FVSETE...	540	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC20038
P02671-540-unknown	FVSETE...	540	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23991
P02671-540-unknown	FVSETE...	540		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-540-unknown	FVSETE...	540	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153862
P02671-541-unknown	VSETES...	541	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4354
P02671-541-unknown	VSETES...	541	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt153880
P02671-548-unknown	GSESGI...	548		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-548-unknown	GSESGI...	548	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180387
P02671-576-unknown	SSSYSK...	576		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-576-unknown	SSSYSK...	576	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180389
P02671-576-unknown	SSSYSK...	576	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02671-578-unknown	SYSKQF...	578		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-578-unknown	SYSKQF...	578	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180391
P02671-582-unknown	QFTSST...	582		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-582-unknown	QFTSST...	582	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180393
P02671-582-unknown	QFTSST...	582	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02671-583-unknown	FTSSTS...	583		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-583-unknown	FTSSTS...	583	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt180395
P02671-592-unknown	GDSTFE...	592	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31968
P02671-592-unknown	GDSTFE...	592	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31978
P02671-592-unknown	GDSTFE...	592		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02671-592-unknown	GDSTFE...	592	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt154497
P02671-602-unknown	KMADEA...	602	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8276
P02671-602-unknown	KMADEA...	602	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt154613

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GTAWTA	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24849
...GTAWTA	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC20034
...GTAWTA	19	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21367
...GEGDFL	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23977
...GEGDFL	27	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt120379
...GGGVRG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27454
...GGGVRG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23713
...GGGVRG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23979
...GGGVRG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21456
...GGGVRG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31739
...GGGVRG	35	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121020
...VRGPRV	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15920
...VRGPRV	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27456
...VRGPRV	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23715
...VRGPRV	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23981
...VRGPRV	38	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121268
...KDSHSL	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21458
...KDSHSL	104	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125856
...ILRGDF	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23983
...ILRGDF	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21460
...ILRGDF	116	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126565
...FSSANN	121	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23717
...FSSANN	121	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21462
...FSSANN	121	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126810
...SANNRD	123	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27458
...SANNRD	123	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt126891
...PGNFKS	238	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4350
...PGNFKS	238	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131414
...QMRMEL	260	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23985
...QMRMEL	260	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132243
...PGGNEI	268	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23987
...PGGNEI	268	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt132488
...GSSERG	367	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16421
...GSSERG	367	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134766
...DWGTFE	413	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4352
...DWGTFE	413	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135628
...PGTRRE	426	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16423
...PGTRRE	426	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135843
...YHTEKL	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC20036
...YHTEKL	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21878
...YHTEKL	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23719
...YHTEKL	432	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21464
...YHTEKL	432	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135930
...KGDKEL	441	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24851
...KGDKEL	441	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21880
...KGDKEL	441	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21369
...KGDKEL	441	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23989
...KGDKEL	441	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136077
...LDGFRH	510	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15922
...LDGFRH	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136964
...PMLGEF	539	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC20038
...PMLGEF	539	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23991
...PMLGEF	539	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137284
...MLGEFV	540	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4354
...MLGEFV	540	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137302
...TSYNRG	591	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31968
...TSYNRG	591	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31978
...TSYNRG	591	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt137919
...ESKSYK	601	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8276
...ESKSYK	601	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt138038
...PLVTQ	866	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP8_HUMAN	19	AWTA.\|.ADSG	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP12_HUMAN	19	AWTA.\|.ADSG	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP13_HUMAN	19	AWTA.\|.ADSG	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP7_HUMAN	27	GDFL.\|.LAEG	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
PLMN_HUMAN	35	GVRG.\|.GPRV	inferred from experiment	unknown	MEROPS	Traynelis SF	Yuan H et al.:The serine protease plasmin cle... (S01.233)	19240037,
MMP3_HUMAN	35	GVRG.\|.GPRV	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP7_HUMAN	35	GVRG.\|.GPRV	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP14_HUMAN	35	GVRG.\|.GPRV	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
THRB_HUMAN	35	GVRG.\|.GPRV	inferred from experiment	unknown	MEROPS	Colby TJ	Lord ST et al.:Analysis of fibrinogen A alpha-... (S01.217)	2404012,
KLK14_HUMAN	38	GPRV.\|.VVER	inferred from experiment	unknown	MEROPS	Diamandis EP	Borgono CA et al.:Expression and functional chara... (S01.029)	17110383,
PLMN_HUMAN	38	GPRV.\|.VVER	inferred from experiment	unknown	MEROPS	Traynelis SF	Yuan H et al.:The serine protease plasmin cle... (S01.233)	19240037,
MMP3_HUMAN	38	GPRV.\|.VVER	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP7_HUMAN	38	GPRV.\|.VVER	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP14_HUMAN	104	SHSL.\|.LTTN	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP7_HUMAN	116	RGDF.\|.FSSA	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP14_HUMAN	116	RGDF.\|.FSSA	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP3_HUMAN	121	SANN.\|.NRDN	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP14_HUMAN	121	SANN.\|.NRDN	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
PLMN_HUMAN	123	NNRD.\|.DNTY	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
CATD_HUMAN	238	NFKS.\|.SQLQ	inferred from experiment	unknown	MEROPS	Loscalzo J	Simon DI et al.:The fibrin(ogen)olytic properti... (A01.009)	8204591,
MMP7_HUMAN	260	RMEL.\|.LERP	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP7_HUMAN	268	GNEI.\|.ITRG	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
KLK5_HUMAN	367	SERG.\|.GSAG	inferred from experiment	unknown	MEROPS	Diamandis EP	Michael IP et al.:Biochemical and enzymatic chara... (S01.017)	15713679,
CATD_HUMAN	413	GTFE.\|.EEVS	inferred from experiment	unknown	MEROPS	Loscalzo J	Simon DI et al.:The fibrin(ogen)olytic properti... (A01.009)	8204591,
KLK5_HUMAN	426	TRRE.\|.EYHT	inferred from experiment	unknown	MEROPS	Diamandis EP	Michael IP et al.:Biochemical and enzymatic chara... (S01.017)	15713679,
MMP12_HUMAN	432	TEKL.\|.LVTS	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP26_HUMAN	432	TEKL.\|.LVTS	inferred from experiment	unknown	MEROPS	Sang QX	Park HI et al.:Peptide substrate specificities... (M10.029)	12119297,
MMP3_HUMAN	432	TEKL.\|.LVTS	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
MMP14_HUMAN	432	TEKL.\|.LVTS	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP8_HUMAN	441	DKEL.\|.LRTG	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP26_HUMAN	441	DKEL.\|.LRTG	inferred from experiment	unknown	MEROPS	Sang QX	Park HI et al.:Peptide substrate specificities... (M10.029)	12119297,
MMP13_HUMAN	441	DKEL.\|.LRTG	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP7_HUMAN	441	DKEL.\|.LRTG	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
KLK14_HUMAN	510	GFRH.\|.HRHP	inferred from experiment	unknown	MEROPS	Diamandis EP	Borgono CA et al.:Expression and functional chara... (S01.029)	17110383,
MMP12_HUMAN	539	LGEF.\|.FVSE	inferred from experiment	unknown	MEROPS	Tschesche H	Hiller O et al.:Matrix metalloproteinases colla... (M10.009)	10930399,
MMP7_HUMAN	539	LGEF.\|.FVSE	inferred from experiment	unknown	MEROPS	Kudryk BJ	Bini A et al.:Characterization of stromelysin... (M10.014)	10529239,
CATD_HUMAN	540	GEFV.\|.VSET	inferred from experiment	unknown	MEROPS	Loscalzo J	Simon DI et al.:The fibrin(ogen)olytic properti... (A01.009)	8204591,
TRYB1_HUMAN	591	YNRG.\|.GDST	inferred from experiment	unknown	MEROPS	Johnson DA	Thomas VA et al.:Human mast cell tryptase fibrin... (S01.143)	9485375,
TRYB2_HUMAN	591	YNRG.\|.GDST	inferred from experiment	unknown	MEROPS	Johnson DA	Thomas VA et al.:Human mast cell tryptase fibrin... (S01.143)	9485375,
CBPB2_HUMAN	601	KSYK.\|.KMAD	inferred from experiment	unknown	MEROPS	Enghild JJ	Valnickova Z et al.:Thrombin-activable fibrinolysis... (M14.009)	17138567,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)