TopFIND 4.0

Q96IY4: Carboxypeptidase B2

General Information

Protein names
- Carboxypeptidase B2
- 3.4.17.20 {ECO:0000269|PubMed:10574983}
- Carboxypeptidase U
- CPU
- Plasma carboxypeptidase B
- pCPB
- Thrombin-activable fibrinolysis inhibitor
- TAFI
Gene names CPB2
Organism Homo sapiens
Protease Family M14.009
Protease ID M14.009
Chromosome location
UniProt ID Q96IY4

4

N-termini

2

C-termini

1

Cleavages

22

Substrates

Sequence

        10         20         30         40         50         60 
MKLCSLAVLV PIVLFCEQHV FAFQSGQVLA ALPRTSRQVQ VLQNLTTTYE IVLWQPVTAD 
        70         80         90        100        110        120 
LIVKKKQVHF FVNASDVDNV KAHLNVSGIP CSVLLADVED LIQQQISNDT VSPRASASYY 
       130        140        150        160        170        180 
EQYHSLNEIY SWIEFITERH PDMLTKIHIG SSFEKYPLYV LKVSGKEQAA KNAIWIDCGI 
       190        200        210        220        230        240 
HAREWISPAF CLWFIGHITQ FYGIIGQYTN LLRLVDFYVM PVVNVDGYDY SWKKNRMWRK 
       250        260        270        280        290        300 
NRSFYANNHC IGTDLNRNFA SKHWCEEGAS SSSCSETYCG LYPESEPEVK AVASFLRRNI 
       310        320        330        340        350        360 
NQIKAYISMH SYSQHIVFPY SYTRSKSKDH EELSLVASEA VRAIEKISKN TRYTHGHGSE 
       370        380        390        400        410        420 
TLYLAPGGGD DWIYDLGIKY SFTIELRDTG TYGFLLPERY IKPTCREAFA AVSKIAWHVI 
   
RNV

Isoforms

- Isoform 2 of Carboxypeptidase B2

Sequence View

        10         20         30         40         50         60 
MKLCSLAVLV PIVLFCEQHV FAFQSGQVLA ALPRTSRQVQ VLQNLTTTYE IVLWQPVTAD 
        70         80         90        100        110        120 
LIVKKKQVHF FVNASDVDNV KAHLNVSGIP CSVLLADVED LIQQQISNDT VSPRASASYY 
       130        140        150        160        170        180 
EQYHSLNEIY SWIEFITERH PDMLTKIHIG SSFEKYPLYV LKVSGKEQAA KNAIWIDCGI 
       190        200        210        220        230        240 
HAREWISPAF CLWFIGHITQ FYGIIGQYTN LLRLVDFYVM PVVNVDGYDY SWKKNRMWRK 
       250        260        270        280        290        300 
NRSFYANNHC IGTDLNRNFA SKHWCEEGAS SSSCSETYCG LYPESEPEVK AVASFLRRNI 
       310        320        330        340        350        360 
NQIKAYISMH SYSQHIVFPY SYTRSKSKDH EELSLVASEA VRAIEKISKN TRYTHGHGSE 
       370        380        390        400        410        420 
TLYLAPGGGD DWIYDLGIKY SFTIELRDTG TYGFLLPERY IKPTCREAFA AVSKIAWHVI 
   
RNV



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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 22 Substrates

N-termini

C-termini

Cleavages

Substrates