P20231: Tryptase beta-2
Protein names | - Tryptase beta-2 - Tryptase-2 - 3.4.21.59 - Tryptase II |
---|---|
Gene names | TPSB2 |
Organism | Homo sapiens |
Protease Family | https://www.ebi.ac.uk/merops/cgi-bin/famsum?family= |
Protease ID | |
Chromosome location | |
UniProt ID | P20231 |
2
N-termini
1
C-termini
0
Cleavages
2
Substrates
Sequence
10 20 30 40 50 60
MLNLLLLALP VLASRAYAAP APGQALQRVG IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG
70 80 90 100 110 120
GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA
130 140 150 160 170 180
DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV
190 200 210 220 230 240
PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG
250 260 270
VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 2 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P20231-19-unknown | APAPGQ... | 19 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P20231-31-unknown | IVGGQE... | 31 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VPKKP | 275 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
FIBA_HUMAN | 591 | YNRG.|.GDST | inferred from experiment | unknown | MEROPS | Johnson DA | Thomas VA et al.:Human mast cell tryptase fibrin... (S01.143) | 9485375, |
FIBA-Isoform2_HUMAN | 591 | YNRG.|.GDST | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC31978 |