TopFIND 4.0

Q15661: Tryptase alpha/beta-1

General Information

Protein names
- Tryptase alpha/beta-1
- Tryptase-1
- 3.4.21.59
- Tryptase I
- Tryptase alpha-1
Gene names TPSAB1
Organism Homo sapiens
Protease Family S01.143
Protease ID S01.143
Chromosome location
UniProt ID Q15661

4

N-termini

1

C-termini

0

Cleavages

13

Substrates

Sequence

        10         20         30         40         50         60 
MLNLLLLALP VLASRAYAAP APGQALQRVG IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG 
        70         80         90        100        110        120 
GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA 
       130        140        150        160        170        180 
DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV 
       190        200        210        220        230        240 
PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG 
       250        260        270    
VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKP

Isoforms

- Isoform 2 of Tryptase alpha/beta-1

Sequence View

        10         20         30         40         50         60 
MLNLLLLALP VLASRAYAAP APGQALQRVG IVGGQEAPRS KWPWQVSLRV HGPYWMHFCG 
        70         80         90        100        110        120 
GSLIHPQWVL TAAHCVGPDV KDLAALRVQL REQHLYYQDQ LLPVSRIIVH PQFYTAQIGA 
       130        140        150        160        170        180 
DIALLELEEP VNVSSHVHTV TLPPASETFP PGMPCWVTGW GDVDNDERLP PPFPLKQVKV 
       190        200        210        220        230        240 
PIMENHICDA KYHLGAYTGD DVRIVRDDML CAGNTRRDSC QGDSGGPLVC KVNGTWLQAG 
       250        260        270    
VVSWGEGCAQ PNRPGIYTRV TYYLDWIHHY VPKKP



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 13 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VPKKP 275 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VPKKP 275 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88855

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates