Q9Y337: Kallikrein-5 {ECO:0000312|HGNC:HGNC:6366}
Protein names | - Kallikrein-5 {ECO:0000312|HGNC:HGNC:6366} - 3.4.21.- - Kallikrein-like protein 2 - KLK-L2 - Stratum corneum tryptic enzyme |
---|---|
Gene names | KLK5 |
Organism | Homo sapiens |
Protease Family | S01.017 |
Protease ID | S01.017 |
Chromosome location | |
UniProt ID | Q9Y337 |
2
N-termini
3
C-termini
10
Cleavages
95
Substrates
Sequence
10 20 30 40 50 60
MATARPPWMW VLCALITALL LGVTEHVLAN NDVSCDHPSN TVPSGSNQDL GAGAGEDARS
70 80 90 100 110 120
DDSSSRIING SDCDMHTQPW QAALLLRPNQ LYCGAVLVHP QWLLTAAHCR KKVFRVRLGH
130 140 150 160 170 180
YSLSPVYESG QQMFQGVKSI PHPGYSHPGH SNDLMLIKLN RRIRPTKDVR PINVSSHCPS
190 200 210 220 230 240
AGTKCLVSGW GTTKSPQVHF PKVLQCLNIS VLSQKRCEDA YPRQIDDTMF CAGDKAGRDS
250 260 270 280 290
CQGDSGGPVV CNGSLQGLVS WGDYPCARPN RPGVYTNLCK FTKWIQETIQ ANS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 10 Cleavages - 95 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9Y337-23-unknown | VTEHVL... | 23 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16399 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15904 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16682 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16494 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16242 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16024 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15817 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15852 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16114 | |||
Q9Y337-67-unknown | IINGSD... | 67 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16639 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16399 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15904 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16682 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16494 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16242 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16024 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15817 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC15852 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16114 | |||
...DSSSRI | 66 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC16639 | |||
...PKVLQC | 205 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000469439 | |||
...IQANS | 293 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |