TopFIND 4.0

P20151: Kallikrein-2

General Information

Protein names
- Kallikrein-2
- 3.4.21.35
- Glandular kallikrein-1
- hGK-1
- Tissue kallikrein-2

Gene names KLK2
Organism Homo sapiens
Protease Family S01.161
Protease ID S01.161
Chromosome location
UniProt ID P20151

8

N-termini

7

C-termini

14

Cleavages

85

Substrates

Sequence

        10         20         30         40         50         60 
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV 
        70         80         90        100        110        120 
LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD 
       130        140        150        160        170        180 
LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS 
       190        200        210        220        230        240 
NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP 
       250        260    
AVYTKVVHYR KWIKDTIAAN P

Isoforms

- Isoform 2 of Kallikrein-2 - Isoform 3 of Kallikrein-2 - Isoform 4 of Kallikrein-2

Sequence View

        10         20         30         40         50         60 
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV 
        70         80         90        100        110        120 
LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD 
       130        140        150        160        170        180 
LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS 
       190        200        210        220        230        240 
NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP 
       250        260    
AVYTKVVHYR KWIKDTIAAN P         10         20         30         40         50         60 
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV 
        70         80         90        100        110        120 
LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD 
       130        140        150        160        170        180 
LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS 
       190        200        210        220        230        240 
NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP 
       250        260    
AVYTKVVHYR KWIKDTIAAN P         10         20         30         40         50         60 
MWDLVLSIAL SVGCTGAVPL IQSRIVGGWE CEKHSQPWQV AVYSHGWAHC GGVLVHPQWV 
        70         80         90        100        110        120 
LTAAHCLKKN SQVWLGRHNL FEPEDTGQRV PVSHSFPHPL YNMSLLKHQS LRPDEDSSHD 
       130        140        150        160        170        180 
LMLLRLSEPA KITDVVKVLG LPTQEPALGT TCYASGWGSI EPEEFLRPRS LQCVSLHLLS 
       190        200        210        220        230        240 
NDMCARAYSE KVTEFMLCAG LWTGGKDTCG GDSGGPLVCN GVLQGITSWG PEPCALPEKP 
       250        260    
AVYTKVVHYR KWIKDTIAAN P



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Protein Neighborhood

Domains & Features

8 N-termini - 7 C-termini - 14 Cleavages - 85 Substrates

N-termini

C-termini

Cleavages

Substrates