TopFIND 4.0

O60259: Kallikrein-8

General Information

Protein names
- Kallikrein-8
- hK8
- 3.4.21.118
- Neuropsin
- NP
- Ovasin
- Serine protease 19
- Serine protease TADG-14
- Tumor-associated differentially expressed gene 14 protein
Gene names KLK8
Organism Homo sapiens
Protease Family S01.244
Protease ID S01.244
Chromosome location
UniProt ID O60259

3

N-termini

2

C-termini

2

Cleavages

43

Substrates

Sequence

        10         20         30         40         50         60 
MGRPRPRAAK TWMFLLLLGG AWAGHSRAQE DKVLGGHECQ PHSQPWQAAL FQGQQLLCGG 
        70         80         90        100        110        120 
VLVGGNWVLT AAHCKKPKYT VRLGDHSLQN KDGPEQEIPV VQSIPHPCYN SSDVEDHNHD 
       130        140        150        160        170        180 
LMLLQLRDQA SLGSKVKPIS LADHCTQPGQ KCTVSGWGTV TSPRENFPDT LNCAEVKIFP 
       190        200        210        220        230        240 
QKKCEDAYPG QITDGMVCAG SSKGADTCQG DSGGPLVCDG ALQGITSWGS DPCGRSDKPG 
       250        260    
VYTNICRYLD WIKKIIGSKG 

Isoforms

- Isoform 2 of Kallikrein-8 - Isoform 3 of Kallikrein-8 - Isoform 4 of Kallikrein-8

Sequence View

        10         20         30         40         50         60 
MGRPRPRAAK TWMFLLLLGG AWAGHSRAQE DKVLGGHECQ PHSQPWQAAL FQGQQLLCGG 
        70         80         90        100        110        120 
VLVGGNWVLT AAHCKKPKYT VRLGDHSLQN KDGPEQEIPV VQSIPHPCYN SSDVEDHNHD 
       130        140        150        160        170        180 
LMLLQLRDQA SLGSKVKPIS LADHCTQPGQ KCTVSGWGTV TSPRENFPDT LNCAEVKIFP 
       190        200        210        220        230        240 
QKKCEDAYPG QITDGMVCAG SSKGADTCQG DSGGPLVCDG ALQGITSWGS DPCGRSDKPG 
       250        260    
VYTNICRYLD WIKKIIGSKG          10         20         30         40         50         60 
MGRPRPRAAK TWMFLLLLGG AWAGHSRAQE DKVLGGHECQ PHSQPWQAAL FQGQQLLCGG 
        70         80         90        100        110        120 
VLVGGNWVLT AAHCKKPKYT VRLGDHSLQN KDGPEQEIPV VQSIPHPCYN SSDVEDHNHD 
       130        140        150        160        170        180 
LMLLQLRDQA SLGSKVKPIS LADHCTQPGQ KCTVSGWGTV TSPRENFPDT LNCAEVKIFP 
       190        200        210        220        230        240 
QKKCEDAYPG QITDGMVCAG SSKGADTCQG DSGGPLVCDG ALQGITSWGS DPCGRSDKPG 
       250        260    
VYTNICRYLD WIKKIIGSKG          10         20         30         40         50         60 
MGRPRPRAAK TWMFLLLLGG AWAGHSRAQE DKVLGGHECQ PHSQPWQAAL FQGQQLLCGG 
        70         80         90        100        110        120 
VLVGGNWVLT AAHCKKPKYT VRLGDHSLQN KDGPEQEIPV VQSIPHPCYN SSDVEDHNHD 
       130        140        150        160        170        180 
LMLLQLRDQA SLGSKVKPIS LADHCTQPGQ KCTVSGWGTV TSPRENFPDT LNCAEVKIFP 
       190        200        210        220        230        240 
QKKCEDAYPG QITDGMVCAG SSKGADTCQG DSGGPLVCDG ALQGITSWGS DPCGRSDKPG 
       250        260    
VYTNICRYLD WIKKIIGSKG 



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 2 Cleavages - 43 Substrates

N-termini

C-termini

Cleavages

Substrates