Q9NRE1: Matrix metalloproteinase-26
Protein names | - Matrix metalloproteinase-26 - MMP-26 - 3.4.24.- - Endometase - Matrilysin-2 |
---|---|
Gene names | MMP26 |
Organism | Homo sapiens |
Protease Family | M10.029 |
Protease ID | M10.029 |
Chromosome location | |
UniProt ID | Q9NRE1 |
5
N-termini
4
C-termini
3
Cleavages
31
Substrates
Sequence
10 20 30 40 50 60
MQLVILRVTI FLPWCFAVPV PPAADHKGWD FVEGYFHQFF LTKKESPLLT QETQTQLLQQ
70 80 90 100 110 120
FHRNGTDLLD MQMHALLHQP HCGVPDGSDT SISPGRCKWN KHTLTYRIIN YPHDMKPSAV
130 140 150 160 170 180
KDSIYNAVSI WSNVTPLIFQ QVQNGDADIK VSFWQWAHED GWPFDGPGGI LGHAFLPNSG
190 200 210 220 230 240
NPGVVHFDKN EHWSASDTGY NLFLVATHEI GHSLGLQHSG NQSSIMYPTY WYHDPRTFQL
250 260
SADDIQRIQH LYGEKCSSDI P
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 4 C-termini - 3 Cleavages - 31 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9NRE1-18-unknown | VPVPPA... | 18 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9NRE1-50-unknown | TQETQT... | 50 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21904 | |||
Q9NRE1-60-unknown | QFHRNG... | 60 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21905 | |||
Q9NRE1-76-unknown | LLHQPH... | 76 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21906 | |||
Q9NRE1-90-unknown | TSISPG... | 90 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9NRE1-90-unknown | TSISPG... | 90 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ESPLLT | 49 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21904 | |||
...TQLLQQ | 59 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21905 | |||
...MQMHAL | 75 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC21906 | |||
...SSDIP | 261 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MMP26_HUMAN | 49 | PLLT.|.TQET | inferred from experiment | unknown | MEROPS | Sang QX | Lee S et al.:Coordinated peak expression of ... (M10.029) | 16940965, |
MMP26_HUMAN | 59 | LLQQ.|.QFHR | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
MMP26_HUMAN | 75 | MHAL.|.LLHQ | inferred from experiment | unknown | MEROPS | Sang QX | Lee S et al.:Coordinated peak expression of ... (M10.029) | 16940965, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
FINC_HUMAN | 44 | PVAV.|.VSQS | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
FINC-Isoform9_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform8_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform7_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform6_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform5_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform4_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform3_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform2_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform17_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform16_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform15_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform14_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform13_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform12_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform11_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
FINC-Isoform10_HUMAN | 44 | PVAV.|.VSQS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21887 | ||
MMP26_HUMAN | 49 | PLLT.|.TQET | inferred from experiment | unknown | MEROPS | Sang QX | Lee S et al.:Coordinated peak expression of ... (M10.029) | 16940965, |
MMP26_HUMAN | 59 | LLQQ.|.QFHR | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
MMP26_HUMAN | 75 | MHAL.|.LLHQ | inferred from experiment | unknown | MEROPS | Sang QX | Lee S et al.:Coordinated peak expression of ... (M10.029) | 16940965, |
MMP9_HUMAN | 93 | LKAM.|.MRTP | inferred from experiment | unknown | MEROPS | Sang QX | Zhao YG et al.:Activation of pro-gelatinase B ... (M10.029) | 12586837, |
FIBG_HUMAN | 103 | KPNM.|.MIDA | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
FIBG-Isoform2_HUMAN | 103 | KPNM.|.MIDA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21882 | ||
VTNC_HUMAN | 134 | PEGI.|.IDSR | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
IBP1_HUMAN | 165 | ALHV.|.VTNI | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
A1AT_HUMAN | 376 | AMFL.|.LEAI | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
A1AT_HUMAN | 381 | AIPM.|.MSIP | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
FIBA-Isoform2_HUMAN | 432 | TEKL.|.LVTS | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21878 | ||
FIBA_HUMAN | 432 | TEKL.|.LVTS | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
FIBA_HUMAN | 441 | DKEL.|.LRTG | inferred from experiment | unknown | MEROPS | Sang QX | Park HI et al.:Peptide substrate specificities... (M10.029) | 12119297, |
FIBA-Isoform2_HUMAN | 441 | DKEL.|.LRTG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC21880 |