Q16663: C-C motif chemokine 15

General Information

Protein names	- C-C motif chemokine 15 - Chemokine CC-2 - HCC-2 - Leukotactin-1 - LKN-1 - MIP-1 delta - Macrophage inflammatory protein 5 - MIP-5 - Mrp-2b - NCC-3 - Small-inducible cytokine A15 - CCL15(22-92) - CCL15(25-92) - CCL15(29-92)
Gene names	CCL15
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q16663

12 N-termini

11 C-termini

28 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MKVSVAALSC LMLVAVLGSQ AQFINDAETE LMMSKLPLEN PVVLNSFHFA ADCCTSYISQ
70 80 90 100 110
SIPCSLMKSY FETSSECSKP GVIFLTKKGR QVCAKPSGPG VQDCMKKLKP YSI

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

12 N-termini - 11 C-termini - 28 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q16663-14-unknown	VAVLGS...	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34888
Q16663-14-unknown	VAVLGS...	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34908
Q16663-14-unknown	VAVLGS...	14	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34926
Q16663-17-unknown	LGSQAQ...	17	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34947
Q16663-17-unknown	LGSQAQ...	17	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34977
Q16663-22-unknown	QFINDA...	22	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34841
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34862
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34885
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34925
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34945
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34976
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35006
Q16663-25-unknown	NDAETE...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35041
Q16663-27-unknown	AETELM...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34887
Q16663-27-unknown	AETELM...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34907
Q16663-27-unknown	AETELM...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34927
Q16663-27-unknown	AETELM...	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35042
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34863
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34886
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34928
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34946
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35007
Q16663-28-unknown	ETELMM...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35022
Q16663-43-unknown	VLNSFH...	43	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16663-43-unknown	VLNSFH...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9512
Q16663-45-unknown	NSFHFA...	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4943
Q16663-46-unknown	SFHFAA...	46	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16663-48-unknown	HFAADC...	48	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4944
Q16663-50-unknown	AADCCT...	50	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q16663-50-unknown	AADCCT...	50	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4945
Q16663-89-unknown	GRQVCA...	89	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34978

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SCLMLV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34888
...SCLMLV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34908
...SCLMLV	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34926
...MLVAVL	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34947
...MLVAVL	16	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34977
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34841
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34862
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34885
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34925
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34945
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34976
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35006
...QAQFIN	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35041
...QFINDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34887
...QFINDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34907
...QFINDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34927
...QFINDA	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35042
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34863
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34886
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34928
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34946
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35007
...FINDAE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35022
...LENPVV	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9512
...NPVVLN	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4943
...VLNSFH	47	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4944
...NSFHFA	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4945
...FLTKKG	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34978
...KPYSI	113	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP13_HUMAN	13	LMLV.\|.VAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP14_HUMAN	13	LMLV.\|.VAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	13	LMLV.\|.VAVL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	16	VAVL.\|.LGSQ		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	16	VAVL.\|.LGSQ		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP1_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP12_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP13_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP8_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP25_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP13_HUMAN	26	INDA.\|.AETE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP14_HUMAN	26	INDA.\|.AETE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	26	INDA.\|.AETE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP25_HUMAN	26	INDA.\|.AETE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP12_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP13_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP8_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP9_HUMAN	27	NDAE.\|.ETEL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
ELNE_HUMAN	42	NPVV.\|.VLNS	inferred from experiment	unknown	MEROPS	Forssmann U	Richter R et al.:Quantum proteolytic activation ... (S01.133)	16034099,
CATG_HUMAN	44	VVLN.\|.NSFH	inferred from experiment	unknown	MEROPS	Forssmann U	Richter R et al.:Quantum proteolytic activation ... (S01.133)	16034099,
CATG_HUMAN	47	NSFH.\|.HFAA	inferred from experiment	unknown	MEROPS	Forssmann U	Richter R et al.:Quantum proteolytic activation ... (S01.133)	16034099,
CATG_HUMAN	49	FHFA.\|.AADC	inferred from experiment	unknown	MEROPS	Forssmann U	Richter R et al.:Quantum proteolytic activation ... (S01.133)	16034099,
MMP7_HUMAN	88	TKKG.\|.GRQV		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)