TopFIND 4.0

P29279: CCN family member 2 {ECO:0000305}

General Information

Protein names
- CCN family member 2 {ECO:0000305}
- Cellular communication network factor 2 {ECO:0000312|HGNC:HGNC:2500}
- Connective tissue growth factor {ECO:0000303|PubMed:1654338}
- Hypertrophic chondrocyte-specific protein 24 {ECO:0000303|PubMed:10614647}
- Insulin-like growth factor-binding protein 8
- IBP-8
- IGF-binding protein 8
- IGFBP-8
Gene names CTGF
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P29279

8

N-termini

7

C-termini

15

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTAASMGPVR VAFVVLLALC SRPAVGQNCS GPCRCPDEPA PRCPAGVSLV LDGCGCCRVC 
        70         80         90        100        110        120 
AKQLGELCTE RDPCDPHKGL FCHFGSPANR KIGVCTAKDG APCIFGGTVY RSGESFQSSC 
       130        140        150        160        170        180 
KYQCTCLDGA VGCMPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DQTVVGPALA 
       190        200        210        220        230        240 
AYRLEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNASCRL EKQSRLCMVR 
       250        260        270        280        290        300 
PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT 
       310        320        330        340    
LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA

Isoforms

- Isoform 2 of Connective tissue growth factor - Isoform 2 of CCN family member 2

Sequence View

        10         20         30         40         50         60 
MTAASMGPVR VAFVVLLALC SRPAVGQNCS GPCRCPDEPA PRCPAGVSLV LDGCGCCRVC 
        70         80         90        100        110        120 
AKQLGELCTE RDPCDPHKGL FCHFGSPANR KIGVCTAKDG APCIFGGTVY RSGESFQSSC 
       130        140        150        160        170        180 
KYQCTCLDGA VGCMPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DQTVVGPALA 
       190        200        210        220        230        240 
AYRLEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNASCRL EKQSRLCMVR 
       250        260        270        280        290        300 
PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT 
       310        320        330        340    
LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA         10         20         30         40         50         60 
MTAASMGPVR VAFVVLLALC SRPAVGQNCS GPCRCPDEPA PRCPAGVSLV LDGCGCCRVC 
        70         80         90        100        110        120 
AKQLGELCTE RDPCDPHKGL FCHFGSPANR KIGVCTAKDG APCIFGGTVY RSGESFQSSC 
       130        140        150        160        170        180 
KYQCTCLDGA VGCMPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DQTVVGPALA 
       190        200        210        220        230        240 
AYRLEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNASCRL EKQSRLCMVR 
       250        260        270        280        290        300 
PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT 
       310        320        330        340    
LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

8 N-termini - 7 C-termini - 15 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)