TopFIND 4.0

P51671: Eotaxin

General Information

Protein names	- Eotaxin - C-C motif chemokine 11 - Eosinophil chemotactic protein - Small-inducible cytokine A11
Gene names	CCL11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P51671

3

N-termini

3

C-termini

4

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MKVSAALLWL LLIAAAFSPQ GLAGPASVPT TCCFNLANRK IPLQRLESYR RITSGKCPQK
70 80 90
AVIFKTKLAK DICADPKKKW VQDSMKYLDQ KSPTPKP

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P51671-10-unknown	LLLIAA...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34872
P51671-10-unknown	LLLIAA...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34932
P51671-10-unknown	LLLIAA...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34988
P51671-24-unknown	GPASVP...	24		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P51671-26-unknown	ASVPTT...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8500

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...AALLWL	9	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34872
	...AALLWL	9	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34932
	...AALLWL	9	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34988
	...GLAGPA	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8500
	...PTPKP	97	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP12_HUMAN	9	LLWL.\|.LLLI		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	9	LLWL.\|.LLLI		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	9	LLWL.\|.LLLI		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
DPP4_HUMAN	25	AGPA.\|.ASVP	inferred from experiment	unknown	MEROPS	De Meester I	Lambeir AM et al.:Kinetic investigation of chemok... (S09.003)	11390394,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)