P11226: Mannose-binding protein C

General Information

Protein names	- Mannose-binding protein C - MBP-C - Collectin-1 - MBP1 - Mannan-binding protein - Mannose-binding lectin
Gene names	MBL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P11226

5 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSLFPSLPLL LLSMVAASYS ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG
        70         80         90        100        110        120
EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA
       130        140        150        160        170        180
RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE
       190        200        210        220        230        240
EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH

LAVCEFPI

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
P11226-21-unknown	ETVTCE...	21	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P11226-68-unknown	GLQGPP...	68		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P11226-69-unknown	LQGPPG...	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21525
P11226-75-unknown	KLGPPG...	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25675
P11226-75-unknown	KLGPPG...	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22679
P11226-93-unknown	QKGDPG...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25676
P11226-93-unknown	QKGDPG...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22680

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QGLRGL	68	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21525
...QGPPGK	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25675
...QGPPGK	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22679
...PGPKGQ	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25676
...PGPKGQ	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22680
...CEFPI	248	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP14_HUMAN	68	LRGL.\|.LQGP	inferred from experiment	unknown	MEROPS	Overall CM	Butler GS et al.:Mannose-binding lectin (MBL) mu... (M10.014)	11891230,
MMP9_HUMAN	74	PPGK.\|.KLGP	inferred from experiment	unknown	MEROPS	Overall CM	Butler GS et al.:Mannose-binding lectin (MBL) mu... (M10.004)	11891230,
MMP2_HUMAN	74	PPGK.\|.KLGP	inferred from experiment	unknown	MEROPS	Overall CM	Butler GS et al.:Mannose-binding lectin (MBL) mu... (M10.014)	11891230,
MMP9_HUMAN	92	PKGQ.\|.QKGD	inferred from experiment	unknown	MEROPS	Overall CM	Butler GS et al.:Mannose-binding lectin (MBL) mu... (M10.014)	11891230,
MMP2_HUMAN	92	PKGQ.\|.QKGD	inferred from experiment	unknown	MEROPS	Overall CM	Butler GS et al.:Mannose-binding lectin (MBL) mu... (M10.014)	11891230,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)