TopFIND 4.0

P09341: Growth-regulated alpha protein

General Information

Protein names	- Growth-regulated alpha protein - C-X-C motif chemokine 1 - GRO-alpha(1-73) - Melanoma growth stimulatory activity - MGSA - Neutrophil-activating protein 3 - NAP-3 - GRO-alpha(4-73) - GRO-alpha(5-73) - GRO-alpha(6-73)
Gene names	CXCL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P09341

6

N-termini

4

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MARAALSAAP SNPRLLRVAL LLLLLVAAGR RAAGASVATE LRCQCLQTLQ GIHPKNIQSV
70 80 90 100
NVKSPGPHCA QTEVIATLKN GRKACLNPAS PIVKKIIEKM LNSDKSN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P09341-35-unknown	ASVATE...	35		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09341-38-unknown	ATELRC...	38		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09341-39-unknown	TELRCQ...	39		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09341-40-unknown	ELRCQC...	40		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P09341-41-unknown	LRCQCL...	41		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25665
P09341-62-unknown	VKSPGP...	62		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25666

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...SVATEL	40	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25665
	...IQSVNV	61	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25666
	...SDKSN	107	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...SDKSN	107		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
	...SDKSN	107		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP9_HUMAN	40	ATEL.\|.LRCQ	inferred from experiment	unknown	MEROPS	Opdenakker G	Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)	14550288,
MMP9_HUMAN	61	SVNV.\|.VKSP	inferred from experiment	unknown	MEROPS	Opdenakker G	Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)	14550288,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)