P02745: Complement C1q subcomponent subunit A

General Information

Protein names	- Complement C1q subcomponent subunit A
Gene names	C1QA
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02745

4 N-termini

5 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGPRGWLVL CVLAISLASM VTEDLCRAPD GKKGEAGRPG RRGRPGLKGE QGEPGAPGIR
        70         80         90        100        110        120
TGIQGLKGDQ GEPGPSGNPG KVGYPGPSGP LGARGIPGIK GTKGSPGNIK DQPRPAFSAI
       130        140        150        160        170        180
RRNPPMGGNV VIFDTVITNQ EEPYQNHSGR FVCTVPGYYY FTFQVLSQWE ICLSIVSSSR
       190        200        210        220        230        240
GQVRRSLGFC DTTNKGLFQV VSGGMVLQLQ QGDQVWVEKD PKKGHIYQGS EADSVFSGFL

IFPSA

Isoforms

Sequence View

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Methodology:

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Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P02745-23-unknown	EDLCRA...	23	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P02745-66-unknown	LKGDQG...	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22206
P02745-93-unknown	ARGIPG...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23729
P02745-93-unknown	ARGIPG...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22207
P02745-93-unknown	ARGIPG...	93	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25323
P02745-109-unknown	IKDQPR...	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23730
P02745-109-unknown	IKDQPR...	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21727

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TGIQGL	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22206
...SGPLGA	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23729
...SGPLGA	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22207
...SGPLGA	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC25323
...GSPGNI	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23730
...GSPGNI	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21727
...WVEKDP	220	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416841
...IFPSA	245	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_HUMAN	65	IQGL.\|.LKGD	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP3_HUMAN	92	PLGA.\|.ARGI	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP2_HUMAN	92	PLGA.\|.ARGI	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP9_HUMAN	92	PLGA.\|.ARGI	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP3_HUMAN	108	PGNI.\|.IKDQ	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP1_HUMAN	108	PGNI.\|.IKDQ	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)