P98073: Enteropeptidase
Protein names | - Enteropeptidase - 3.4.21.9 - Enterokinase - Serine protease 7 - Transmembrane protease serine 15 - Enteropeptidase non-catalytic heavy chain - Enteropeptidase catalytic light chain |
---|---|
Gene names | TMPRSS15 |
Organism | Homo sapiens |
Protease Family | S01.156 |
Protease ID | S01.156 |
Chromosome location | |
UniProt ID | P98073 |
2
N-termini
3
C-termini
0
Cleavages
3
Substrates
Sequence
10 20 30 40 50 60
MGSKRGISSR HHSLSSYEIM FAALFAILVV LCAGLIAVSC LTIKESQRGA ALGQSHEARA
70 80 90 100 110 120
TFKITSGVTY NPNLQDKLSV DFKVLAFDLQ QMIDEIFLSS NLKNEYKNSR VLQFENGSII
130 140 150 160 170 180
VVFDLFFAQW VSDENVKEEL IQGLEANKSS QLVTFHIDLN SVDILDKLTT TSHLATPGNV
190 200 210 220 230 240
SIECLPGSSP CTDALTCIKA DLFCDGEVNC PDGSDEDNKM CATVCDGRFL LTGSSGSFQA
250 260 270 280 290 300
THYPKPSETS VVCQWIIRVN QGLSIKLSFD DFNTYYTDIL DIYEGVGSSK ILRASIWETN
310 320 330 340 350 360
PGTIRIFSNQ VTATFLIESD ESDYVGFNAT YTAFNSSELN NYEKINCNFE DGFCFWVQDL
370 380 390 400 410 420
NDDNEWERIQ GSTFSPFTGP NFDHTFGNAS GFYISTPTGP GGRQERVGLL SLPLDPTLEP
430 440 450 460 470 480
ACLSFWYHMY GENVHKLSIN ISNDQNMEKT VFQKEGNYGD NWNYGQVTLN ETVKFKVAFN
490 500 510 520 530 540
AFKNKILSDI ALDDISLTYG ICNGSLYPEP TLVPTPPPEL PTDCGGPFEL WEPNTTFSST
550 560 570 580 590 600
NFPNSYPNLA FCVWILNAQK GKNIQLHFQE FDLENINDVV EIRDGEEADS LLLAVYTGPG
610 620 630 640 650 660
PVKDVFSTTN RMTVLLITND VLARGGFKAN FTTGYHLGIP EPCKADHFQC KNGECVPLVN
670 680 690 700 710 720
LCDGHLHCED GSDEADCVRF FNGTTNNNGL VRFRIQSIWH TACAENWTTQ ISNDVCQLLG
730 740 750 760 770 780
LGSGNSSKPI FPTDGGPFVK LNTAPDGHLI LTPSQQCLQD SLIRLQCNHK SCGKKLAAQD
790 800 810 820 830 840
ITPKIVGGSN AKEGAWPWVV GLYYGGRLLC GASLVSSDWL VSAAHCVYGR NLEPSKWTAI
850 860 870 880 890 900
LGLHMKSNLT SPQTVPRLID EIVINPHYNR RRKDNDIAMM HLEFKVNYTD YIQPICLPEE
910 920 930 940 950 960
NQVFPPGRNC SIAGWGTVVY QGTTANILQE ADVPLLSNER CQQQMPEYNI TENMICAGYE
970 980 990 1000 1010
EGGIDSCQGD SGGPLMCQEN NRWFLAGVTS FGYKCALPNR PGVYARVSRF TEWIQSFLH
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 3 C-termini - 0 Cleavages - 3 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P98073-2-unknown | GSKRGI... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P98073-785-unknown | IVGGSN... | 785 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...CQWIIR | 257 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000398253 | |||
...DITPKI | 784 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QSFLH | 1019 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
TRY3-Isoform2_HUMAN | 36 | DDKI.|.IVGG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC9541 | ||
MMP9_HUMAN | 65 | ESKS.|.SLGP | inferred from experiment | unknown | MEROPS | Salo T | Vilen ST et al.:Intracellular co-localization o... (S01.156) | 18062964, |
TRY3_HUMAN | 80 | DDKI.|.IVGG | inferred from experiment | unknown | MEROPS | Bunnett NW | Knecht W et al.:Trypsin IV or mesotrypsin and p... (S01.156) | 17623652, |