TopFIND 4.0

O75531: Barrier-to-autointegration factor

General Information

Protein names	- Barrier-to-autointegration factor - Breakpoint cluster region protein 1 - Barrier-to-autointegration factor, N-terminally processed
Gene names	BANF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75531

5

N-termini

5

C-termini

4

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MTTSQKHRDF VAEPMGEKPV GSLAGIGEVL GKKLEERGFD KAYVVLGQFL VLKKDEDLFR
70 80
EWLKDTCGAN AKQSRDCFGC LREWCDAFL

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75531-1-Acetylation	MTTSQK...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75531-2-Acetylation	TTSQKH...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75531-13-unknown	EPMGEK...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18318
O75531-17-unknown	EKPVGS...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16969
O75531-17-unknown	EKPVGS...	17		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18319
O75531-22-unknown	SLAGIG...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3299

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RDFVAE	12	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18318
	...AEPMGE	16	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC16969
	...AEPMGE	16	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18319
	...EKPVGS	21	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3299
	...AGIGEV	28	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000431785
	...CDAFL	89	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	12	FVAE.\|.EPMG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	16	PMGE.\|.EKPV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	16	PMGE.\|.EKPV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATB_HUMAN	21	PVGS.\|.SLAG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)