TopFIND 4.0

P63313: Thymosin beta-10

General Information

Protein names	- Thymosin beta-10
Gene names	TMSB10
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P63313

10

N-termini

3

C-termini

2

Cleavages

0

Substrates

Sequence

10 20 30 40
MADKPDMGEI ASFDKAKLKK TETQEKNTLP TKETIEQEKR SEIS

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P63313-2-unknown	MADKPD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63313-2-unknown	MADKPD...	1			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P63313-2-	ADKPDM...	2			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P63313-2-Acetylation	ADKPDM...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P63313-7-	MGEIAS...	7			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P63313-7-unknown	MGEIAS...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17802
P63313-21-	TETQEK...	21			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P63313-27-	NTLPTK...	27			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P63313-27-	NTLPTK...	27			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P63313-27-	NTLPTK...	27			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P63313-27-unknown	NTLPTK...	27			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P63313-28-unknown	TLPTKE...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17803
P63313-28-	TLPTKE...	28			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...ADKPDM	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17802
	...TQEKNT	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17803
	...RSEIS	44	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	6	KPDM.\|.MGEI	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	27	EKNT.\|.TLPT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)