Q15582: Transforming growth factor-beta-induced protein ig-h3

General Information

Protein names	- Transforming growth factor-beta-induced protein ig-h3 - Beta ig-h3 - Kerato-epithelin - RGD-containing collagen-associated protein - RGD-CAP
Gene names	TGFBI
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15582

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALFVRLLAL ALALALGPAA TLAGPAKSPY QLVLQHSRLR GRQHGPNVCA VQKVIGTNRK
        70         80         90        100        110        120
YFTNCKQWYQ RKICGKSTVI SYECCPGYEK VPGEKGCPAA LPLSNLYETL GVVGSTTTQL
       130        140        150        160        170        180
YTDRTEKLRP EMEGPGSFTI FAPSNEAWAS LPAEVLDSLV SNVNIELLNA LRYHMVGRRV
       190        200        210        220        230        240
LTDELKHGMT LTSMYQNSNI QIHHYPNGIV TVNCARLLKA DHHATNGVVH LIDKVISTIT
       250        260        270        280        290        300
NNIQQIIEIE DTFETLRAAV AASGLNTMLE GNGQYTLLAP TNEAFEKIPS ETLNRILGDP
       310        320        330        340        350        360
EALRDLLNNH ILKSAMCAEA IVAGLSVETL EGTTLEVGCS GDMLTINGKA IISNKDILAT
       370        380        390        400        410        420
NGVIHYIDEL LIPDSAKTLF ELAAESDVST AIDLFRQAGL GNHLSGSERL TLLAPLNSVF
       430        440        450        460        470        480
KDGTPPIDAH TRNLLRNHII KDQLASKYLY HGQTLETLGG KKLRVFVYRN SLCIENSCIA
       490        500        510        520        530        540
AHDKRGRYGT LFTMDRVLTP PMGTVMDVLK GDNRFSMLVA AIQSAGLTET LNREGVYTVF
       550        560        570        580        590        600
APTNEAFRAL PPRERSRLLG DAKELANILK YHIGDEILVS GGIGALVRLK SLQGDKLEVS
       610        620        630        640        650        660
LKNNVVSVNK EPVAEPDIMA TNGVVHVITN VLQPPANRPQ ERGDELADSA LEIFKQASAF
       670        680
SRASQRSVRL APVYQKLLER MKH

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15582-24-unknown	GPAKSP...	24	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15582-24-unknown	GPAKSP...	24	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q15582-28-unknown	SPYQLV...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17989
Q15582-257-unknown	RAAVAA...	257	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000474155
Q15582-619-unknown	MATNGV...	619	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000423935
Q15582-649-unknown	SALEIF...	649	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19584

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AGPAKS	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17989
...HGQTLE	455	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000423871
...DELADS	648	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19584
...ERMKH	683	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	27	PAKS.\|.SPYQ	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	648	LADS.\|.SALE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)