P16989: Y-box-binding protein 3
Protein names | - Y-box-binding protein 3 - Cold shock domain-containing protein A - DNA-binding protein A - Single-strand DNA-binding protein NF-GMB |
---|---|
Gene names | YBX3 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P16989 |
18
N-termini
3
C-termini
3
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSEAGEATTT TTTTLPQAPT EAAAAAPQDP APKSPVGSGA PQAAAPAPAA HVAGNPGGDA
70 80 90 100 110 120
APAATGTAAA ASLATAAGSE DAEKKVLATK VLGTVKWFNV RNGYGFINRN DTKEDVFVHQ
130 140 150 160 170 180
TAIKKNNPRK YLRSVGDGET VEFDVVEGEK GAEAANVTGP DGVPVEGSRY AADRRRYRRG
190 200 210 220 230 240
YYGRRRGPPR NYAGEEEEEG SGSSEGFDPP ATDRQFSGAR NQLRRPQYRP QYRQRRFPPY
250 260 270 280 290 300
HVGQTFDRRS RVLPHPNRIQ AGEIGEMKDG VPEGAQLQGP VHRNPTYRPR YRSRGPPRPR
310 320 330 340 350 360
PAPAVGEAED KENQQATSGP NQPSVRRGYR RPYNYRRRPR PPNAPSQDGK EAKAGEAPTE
370
NPAPPTQQSS AE
Isoforms
- Isoform 2 of Y-box-binding protein 3 - Isoform 3 of Y-box-binding protein 3Sequence View
10 20 30 40 50 60
MSEAGEATTT TTTTLPQAPT EAAAAAPQDP APKSPVGSGA PQAAAPAPAA HVAGNPGGDA
70 80 90 100 110 120
APAATGTAAA ASLATAAGSE DAEKKVLATK VLGTVKWFNV RNGYGFINRN DTKEDVFVHQ
130 140 150 160 170 180
TAIKKNNPRK YLRSVGDGET VEFDVVEGEK GAEAANVTGP DGVPVEGSRY AADRRRYRRG
190 200 210 220 230 240
YYGRRRGPPR NYAGEEEEEG SGSSEGFDPP ATDRQFSGAR NQLRRPQYRP QYRQRRFPPY
250 260 270 280 290 300
HVGQTFDRRS RVLPHPNRIQ AGEIGEMKDG VPEGAQLQGP VHRNPTYRPR YRSRGPPRPR
310 320 330 340 350 360
PAPAVGEAED KENQQATSGP NQPSVRRGYR RPYNYRRRPR PPNAPSQDGK EAKAGEAPTE
370
NPAPPTQQSS AE
10 20 30 40 50 60
MSEAGEATTT TTTTLPQAPT EAAAAAPQDP APKSPVGSGA PQAAAPAPAA HVAGNPGGDA
70 80 90 100 110 120
APAATGTAAA ASLATAAGSE DAEKKVLATK VLGTVKWFNV RNGYGFINRN DTKEDVFVHQ
130 140 150 160 170 180
TAIKKNNPRK YLRSVGDGET VEFDVVEGEK GAEAANVTGP DGVPVEGSRY AADRRRYRRG
190 200 210 220 230 240
YYGRRRGPPR NYAGEEEEEG SGSSEGFDPP ATDRQFSGAR NQLRRPQYRP QYRQRRFPPY
250 260 270 280 290 300
HVGQTFDRRS RVLPHPNRIQ AGEIGEMKDG VPEGAQLQGP VHRNPTYRPR YRSRGPPRPR
310 320 330 340 350 360
PAPAVGEAED KENQQATSGP NQPSVRRGYR RPYNYRRRPR PPNAPSQDGK EAKAGEAPTE
370
NPAPPTQQSS AE
Protein Neighborhood
Domains & Features
18 N-termini - 3 C-termini - 3 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P16989-1-unknown | MSEAGE... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94854 | |||
P16989-1-unknown | MSEAGE... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt94855 | |||
P16989-2-unknown | MSEAGE... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P16989-2-Acetylation | SEAGEA... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P16989-2-Acetylation | SEAGEA... | 2 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
P16989-2-Acetylation | SEAGEA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110930 | ||
P16989-2-Acetylation | SEAGEA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110931 | ||
P16989-72- | SLATAA... | 72 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P16989-72- | SLATAA... | 72 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P16989-72- | SLATAA... | 72 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-72-unknown | SLATAA... | 72 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P16989-72-unknown | SLATAA... | 72 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161446 | |||
P16989-72-unknown | SLATAA... | 72 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161447 | |||
P16989-75-unknown | TAAGSE... | 75 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5624 | |||
P16989-75-unknown | TAAGSE... | 75 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt141001 | |||
P16989-75-unknown | TAAGSE... | 75 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt141002 | |||
P16989-103- | GYGFIN... | 103 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P16989-103-unknown | GYGFIN... | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175525 | |||
P16989-103-unknown | GYGFIN... | 103 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt175526 | |||
P16989-138- | GETVEF... | 138 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-138-unknown | GETVEF... | 138 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170310 | |||
P16989-138-unknown | GETVEF... | 138 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170311 | |||
P16989-145- | VVEGEK... | 145 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-145-unknown | VVEGEK... | 145 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170304 | |||
P16989-145-unknown | VVEGEK... | 145 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170305 | |||
P16989-148- | GEKGAE... | 148 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-148-unknown | GEKGAE... | 148 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170307 | |||
P16989-148-unknown | GEKGAE... | 148 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt170308 | |||
P16989-162- | GVPVEG... | 162 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P16989-162- | GVPVEG... | 162 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P16989-162- | GVPVEG... | 162 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P16989-162- | GVPVEG... | 162 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-162- | GVPVEG... | 162 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P16989-162-unknown | GVPVEG... | 162 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P16989-162-unknown | GVPVEG... | 162 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161443 | |||
P16989-162-unknown | GVPVEG... | 162 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161444 | |||
P16989-270-unknown | GVPEGA... | 270 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18806 | |||
P16989-270-unknown | GVPEGA... | 270 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17405 | |||
P16989-270-unknown | GVPEGA... | 270 | unknown | Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... | 18722006 | ||||
P16989-270-unknown | GVPEGA... | 270 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt161441 | |||
P16989-270-unknown | GVPEGA... | 270 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149117 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_Etoposide | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apopotic_Jurkat_FasL | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apoptotic_RPMI_Dox | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | RMPI_untreated | 23264352 | |||
P16989-270- | GVPEGA... | 270 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...AASLAT | 74 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5624 | |||
...AASLAT | 74 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt124151 | |||
...AASLAT | 74 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt124152 | |||
...GEMKDG | 269 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC18806 | |||
...GEMKDG | 269 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17405 | |||
...GEMKDG | 269 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132502 | |||
...QSSAE | 372 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...QSSAE | 372 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt90472 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATL1_HUMAN | 74 | SLAT.|.TAAG | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
MEP1B_HUMAN | 269 | MKDG.|.GVPE | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
MEP1A_HUMAN | 269 | MKDG.|.GVPE | inferred from experiment | unknown | MEROPS | Overall CM | Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) | 21693781, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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