P25398: 40S ribosomal protein S12

General Information

Protein names	- 40S ribosomal protein S12 - Small ribosomal subunit protein eS12 {ECO:0000303\|PubMed:24524803}
Gene names	RPS12
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P25398

6 N-termini

3 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC VLASNCDEPM
        70         80         90        100        110        120
YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP RKVVGCSCVV VKDYGKESQA
       130
KDVIEEYFKC KK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P25398-2-unknown	MAEEGI...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P25398-2-Acetylation	AEEGIA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P25398-2-Acetylation	AEEGIA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P25398-2-Acetylation	AEEGIA...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P25398-2-Acetylation	AEEGIA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P25398-12-unknown	MDVNTA...	12		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P25398-13-unknown	DVNTAL...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18976
P25398-13-unknown	DVNTAL...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5721
P25398-13-unknown	DVNTAL...	13		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17531
P25398-66-unknown	EALCAE...	66			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P25398-70-unknown	AEHQIN...	70		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5722

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AGGVMD	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18976
...AGGVMD	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5721
...AGGVMD	12	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17531
...VEALCA	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5722
...FKCKK	132	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	12	GVMD.\|.DVNT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	12	GVMD.\|.DVNT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	12	GVMD.\|.DVNT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	69	ALCA.\|.AEHQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)