Q12797: Aspartyl/asparaginyl beta-hydroxylase

General Information

Protein names	- Aspartyl/asparaginyl beta-hydroxylase - 1.14.11.16 {ECO:0000269\|PubMed:11773073} - Aspartate beta-hydroxylase - ASP beta-hydroxylase - Peptide-aspartate beta-dioxygenase
Gene names	ASPH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q12797

3 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 3 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 4 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 5 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 10 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 6 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 7 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 8 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 9 of Aspartyl/asparaginyl beta-hydroxylase - Isoform 11 of Aspartyl/asparaginyl beta-hydroxylase

Sequence View

        10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI         10         20         30         40         50         60
MAQRKNAKSS GNSSSSGSGS GSTSAGSSSP GARRETKHGG HKNGRKGGLS GTSFFTWFMV
        70         80         90        100        110        120
IALLGVWTSV AVVWFDLVDY EEVLGKLGIY DADGDGDFDV DDAKVLLGLK ERSTSEPAVP
       130        140        150        160        170        180
PEEAEPHTEP EEQVPVEAEP QNIEDEAKEQ IQSLLHEMVH AEHVEGEDLQ QEDGPTGEPQ
       190        200        210        220        230        240
QEDDEFLMAT DVDDRFETLE PEVSHEETEH SYHVEETVSQ DCNQDMEEMM SEQENPDSSE
       250        260        270        280        290        300
PVVEDERLHH DTDDVTYQVY EEQAVYEPLE NEGIEITEVT APPEDNPVED SQVIVEEVSI
       310        320        330        340        350        360
FPVEEQQEVP PETNRKTDDP EQKAKVKKKK PKLLNKFDKT IKAELDAAEK LRKRGKIEEA
       370        380        390        400        410        420
VNAFKELVRK YPQSPRARYG KAQCEDDLAE KRRSNEVLRG AIETYQEVAS LPDVPADLLK
       430        440        450        460        470        480
LSLKRRSDRQ QFLGHMRGSL LTLQRLVQLF PNDTSLKNDL GVGYLLIGDN DNAKKVYEEV
       490        500        510        520        530        540
LSVTPNDGFA KVHYGFILKA QNKIAESIPY LKEGIESGDP GTDDGRFYFH LGDAMQRVGN
       550        560        570        580        590        600
KEAYKWYELG HKRGHFASVW QRSLYNVNGL KAQPWWTPKE TGYTELVKSL ERNWKLIRDE
       610        620        630        640        650        660
GLAVMDKAKG LFLPEDENLR EKGDWSQFTL WQQGRRNENA CKGAPKTCTL LEKFPETTGC
       670        680        690        700        710        720
RRGQIKYSIM HPGTHVWPHT GPTNCRLRMH LGLVIPKEGC KIRCANETKT WEEGKVLIFD
       730        740        750
DSFEHEVWQD ASSFRLIFIV DVWHPELTPQ QRRSLPAI

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q12797-1-unknown	MAQRKN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q12797-1-unknown	MAQRKN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67672
Q12797-1-unknown	MAQRKN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67677
Q12797-1-unknown	MAQRKN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt67678
Q12797-99-unknown	DVDDAK...	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19388
Q12797-99-unknown	DVDDAK...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141595
Q12797-99-unknown	DVDDAK...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141596
Q12797-99-unknown	DVDDAK...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt141597
Q12797-99-unknown	DVDDAK...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142369
Q12797-99-unknown	DVDDAK...	99	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt142370
Q12797-191-unknown	DVDDRF...	191	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17875
Q12797-191-unknown	DVDDRF...	191	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145810
Q12797-191-unknown	DVDDRF...	191	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt145811
Q12797-191-unknown	DVDDRF...	191	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt146297

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GDGDFD	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19388
...GDGDFD	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125561
...GDGDFD	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125562
...GDGDFD	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154339
...FLMATD	190	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17875
...FLMATD	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129107
...FLMATD	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129108
...FLMATD	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129600
...SLPAI	758	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	98	GDFD.\|.DVDD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	190	MATD.\|.DVDD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)