P13797: Plastin-3

General Information

Protein names	- Plastin-3 - T-plastin
Gene names	PLS3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P13797

13 N-termini

12 C-termini

12 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Plastin-3 - Isoform 3 of Plastin-3

Sequence View

        10         20         30         40         50         60
MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKVREIIQKL
        70         80         90        100        110        120
MLDGDRNKDG KISFDEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS
       130        140        150        160        170        180
YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE
       190        200        210        220        230        240
RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF
       250        260        270        280        290        300
ADIELSRNEA LAALLRDGET LEELMKLSPE ELLLRWANFH LENSGWQKIN NFSADIKDSK
       310        320        330        340        350        360
AYFHLLNQIA PKGQKEGEPR IDINMSGFNE TDDLKRAESM LQQADKLGCR QFVTPADVVS
       370        380        390        400        410        420
GNPKLNLAFV ANLFNKYPAL TKPENQDIDW TLLEGETREE RTFRNWMNSL GVNPHVNHLY
       430        440        450        460        470        480
ADLQDALVIL QLYERIKVPV DWSKVNKPPY PKLGANMKKL ENCNYAVELG KHPAKFSLVG
       490        500        510        520        530        540
IGGQDLNDGN QTLTLALVWQ LMRRYTLNVL EDLGDGQKAN DDIIVNWVNR TLSEAGKSTS
       550        560        570        580        590        600
IQSFKDKTIS SSLAVVDLID AIQPGCINYD LVKSGNLTED DKHNNAKYAV SMARRIGARV
       610        620        630
YALPEDLVEV KPKMVMTVFA CLMGRGMKRV         10         20         30         40         50         60
MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKVREIIQKL
        70         80         90        100        110        120
MLDGDRNKDG KISFDEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS
       130        140        150        160        170        180
YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE
       190        200        210        220        230        240
RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF
       250        260        270        280        290        300
ADIELSRNEA LAALLRDGET LEELMKLSPE ELLLRWANFH LENSGWQKIN NFSADIKDSK
       310        320        330        340        350        360
AYFHLLNQIA PKGQKEGEPR IDINMSGFNE TDDLKRAESM LQQADKLGCR QFVTPADVVS
       370        380        390        400        410        420
GNPKLNLAFV ANLFNKYPAL TKPENQDIDW TLLEGETREE RTFRNWMNSL GVNPHVNHLY
       430        440        450        460        470        480
ADLQDALVIL QLYERIKVPV DWSKVNKPPY PKLGANMKKL ENCNYAVELG KHPAKFSLVG
       490        500        510        520        530        540
IGGQDLNDGN QTLTLALVWQ LMRRYTLNVL EDLGDGQKAN DDIIVNWVNR TLSEAGKSTS
       550        560        570        580        590        600
IQSFKDKTIS SSLAVVDLID AIQPGCINYD LVKSGNLTED DKHNNAKYAV SMARRIGARV
       610        620        630
YALPEDLVEV KPKMVMTVFA CLMGRGMKRV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

13 N-termini - 12 C-termini - 12 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P13797-1-unknown	MDEMAT...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P13797-8-unknown	QISKDE...	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7313
P13797-9-unknown	ISKDEL...	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17329
P13797-34-unknown	DYELHE...	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17330
P13797-46-unknown	MPLPGY...	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469895
P13797-46-unknown	MPLPGY...	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472841
P13797-46-unknown	MPLPGY...	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000289290
P13797-46-unknown	MPLPGY...	46	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445339
P13797-108-unknown	GTSELS...	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5595
P13797-114-unknown	SEGTQH...	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7314
P13797-114-unknown	SEGTQH...	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5596
P13797-161-unknown	GDGIVL...	161	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
P13797-354-unknown	TPADVV...	354	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5597
P13797-407-unknown	MNSLGV...	407	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469190
P13797-407-unknown	MNSLGV...	407	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439260
P13797-409-unknown	SLGVNP...	409	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3641
P13797-412-unknown	VNPHVN...	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3642
P13797-412-unknown	VNPHVN...	412	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7315
P13797-603-unknown	LPEDLV...	603	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17331
P13797-603-unknown	LPEDLV...	603	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5598

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EMATTQ	7	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7313
...MATTQI	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17329
...NGFICD	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17330
...ICALGG	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5595
...TSELSS	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7314
...TSELSS	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5596
...PFIIQE	194	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475533
...PFIIQE	194	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475900
...CRQFVT	353	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5597
...RNWMNS	408	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3641
...MNSLGV	411	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3642
...MNSLGV	411	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC7315
...YAVELG	469	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000471952
...YAVELG	469	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000417728
...ARVYAL	602	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17331
...ARVYAL	602	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5598
...GMKRV	630	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	7	ATTQ.\|.QISK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	8	TTQI.\|.ISKD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	33	FICD.\|.DYEL	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	107	ALGG.\|.GTSE	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	113	ELSS.\|.SEGT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	113	ELSS.\|.SEGT	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	353	QFVT.\|.TPAD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	408	WMNS.\|.SLGV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATB_HUMAN	411	SLGV.\|.VNPH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	411	SLGV.\|.VNPH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1A_HUMAN	602	VYAL.\|.LPED	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	602	VYAL.\|.LPED	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)