P57055: Protein ripply3

General Information

Protein names	- Protein ripply3 - Down syndrome critical region protein 6
Gene names	RIPPLY3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P57055

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEPEAAAGAR KARGRGCHCP GDAPWRPPPP RGPESPAPWR PWIQTPGDAE LTRTGRPLEP
        70         80         90        100        110        120
RADQHTFGSK GAFGFQHPVR VYLPMSKRQE YLRSSGEQVL ASFPVQATID FYDDESTESA
       130        140        150        160        170        180
SEAEEPEEGP PPLHLLPQEV GGRQENGPGG KGRDQGINQG QRSSGGGDHW GEGPLPQGVS
       190
SRGGKCSSSK

Isoforms

- Isoform 2 of Protein ripply3

Sequence View

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Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P57055-1-acetylation	MEPEAA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P57055-1-unknown	MEPEAA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P57055-23-unknown	APWRPP...	23		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17753
P57055-85-unknown	MSKRQE...	85		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73274

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HCPGDA	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17753
...CSSSK	190	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...CSSSK	190	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt68892

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	22	PGDA.\|.APWR	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)