Q14247: Src substrate cortactin
Protein names | - Src substrate cortactin - Amplaxin - Oncogene EMS1 |
---|---|
Gene names | CTTN |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q14247 |
8
N-termini
6
C-termini
7
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE
70 80 90 100 110 120
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG
130 140 150 160 170 180
FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG
190 200 210 220 230 240
KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT
250 260 270 280 290 300
DRQDKCALGW DHQEKLQLHE SQKDYKTGFG GKFGVQSERQ DSAAVGFDYK EKLAKHESQQ
310 320 330 340 350 360
DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE
370 380 390 400 410 420
KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV
430 440 450 460 470 480
YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP
490 500 510 520 530 540
AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL
550
FPANYVELRQ
Isoforms
- Isoform 2 of Src substrate cortactin - Isoform 3 of Src substrate cortactinSequence View
10 20 30 40 50 60
MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE
70 80 90 100 110 120
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG
130 140 150 160 170 180
FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG
190 200 210 220 230 240
KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT
250 260 270 280 290 300
DRQDKCALGW DHQEKLQLHE SQKDYKTGFG GKFGVQSERQ DSAAVGFDYK EKLAKHESQQ
310 320 330 340 350 360
DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE
370 380 390 400 410 420
KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV
430 440 450 460 470 480
YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP
490 500 510 520 530 540
AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL
550
FPANYVELRQ
10 20 30 40 50 60
MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE
70 80 90 100 110 120
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG
130 140 150 160 170 180
FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG
190 200 210 220 230 240
KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT
250 260 270 280 290 300
DRQDKCALGW DHQEKLQLHE SQKDYKTGFG GKFGVQSERQ DSAAVGFDYK EKLAKHESQQ
310 320 330 340 350 360
DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE
370 380 390 400 410 420
KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV
430 440 450 460 470 480
YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP
490 500 510 520 530 540
AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL
550
FPANYVELRQ
Protein Neighborhood
Domains & Features
8 N-termini - 6 C-termini - 7 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q14247-1-unknown | MWKASA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q14247-1-unknown | MWKASA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90652 | |||
Q14247-1-unknown | MWKASA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt90653 | |||
Q14247-51-unknown | EHINIH... | 51 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17935 | |||
Q14247-51-unknown | EHINIH... | 51 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19511 | |||
Q14247-51-unknown | EHINIH... | 51 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139237 | |||
Q14247-51-unknown | EHINIH... | 51 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt139239 | |||
Q14247-136- | AVGFEY... | 136 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q14247-136-unknown | AVGFEY... | 136 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172579 | |||
Q14247-136-unknown | AVGFEY... | 136 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt172580 | |||
Q14247-337-unknown | TVPVEA... | 337 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1065 | |||
Q14247-337-unknown | TVPVEA... | 337 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14484 | |||
Q14247-337-unknown | TVPVEA... | 337 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149850 | |||
Q14247-337-unknown | TVPVEA... | 337 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149851 | |||
Q14247-347-unknown | TSNIRA... | 347 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1068 | |||
Q14247-347-unknown | TSNIRA... | 347 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150112 | |||
Q14247-347-unknown | TSNIRA... | 347 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150113 | |||
Q14247-347-unknown | TSNIRA... | 347 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q14247-347-unknown | TSNIRA... | 347 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
Q14247-352-unknown | ANFENL... | 352 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1071 | |||
Q14247-352-unknown | ANFENL... | 352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150215 | |||
Q14247-352-unknown | ANFENL... | 352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150216 | |||
Q14247-359-unknown | KEKEQE... | 359 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1074 | |||
Q14247-359-unknown | KEKEQE... | 359 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150377 | |||
Q14247-359-unknown | KEKEQE... | 359 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150378 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...GSGHQE | 50 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17935 | |||
...GSGHQE | 50 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC19511 | |||
...GSGHQE | 50 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122312 | |||
...GSGHQE | 50 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt122314 | |||
...SAYQKT | 336 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1065 | |||
...SAYQKT | 336 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14484 | |||
...SAYQKT | 336 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133241 | |||
...SAYQKT | 336 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133242 | |||
...AVTSKT | 346 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1068 | |||
...AVTSKT | 346 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133504 | |||
...AVTSKT | 346 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133505 | |||
...TSNIRA | 351 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1071 | |||
...TSNIRA | 351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133609 | |||
...TSNIRA | 351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133610 | |||
...FENLAK | 358 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1074 | |||
...FENLAK | 358 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133774 | |||
...FENLAK | 358 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt133775 | |||
...VELRQ | 550 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...VELRQ | 550 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt86271 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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