Q15029: 116 kDa U5 small nuclear ribonucleoprotein component
Protein names | - 116 kDa U5 small nuclear ribonucleoprotein component - Elongation factor Tu GTP-binding domain-containing protein 2 - SNU114 homolog - hSNU114 - U5 snRNP-specific protein, 116 kDa - U5-116 kDa |
---|---|
Gene names | EFTUD2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q15029 |
8
N-termini
7
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDTDLYDEFG NYIGPELDSD EDDDELGRET KDLDEMDDDD DDDDVGDHDD DHPGMEVVLH
70 80 90 100 110 120
EDKKYYPTAE EVYGPEVETI VQEEDTQPLT EPIIKPVKTK KFTLMEQTLP VTVYEMDFLA
130 140 150 160 170 180
DLMDNSELIR NVTLCGHLHH GKTCFVDCLI EQTHPEIRKR YDQDLCYTDI LFTEQERGVG
190 200 210 220 230 240
IKSTPVTVVL PDTKGKSYLF NIMDTPGHVN FSDEVTAGLR ISDGVVLFID AAEGVMLNTE
250 260 270 280 290 300
RLIKHAVQER LAVTVCINKI DRLILELKLP PTDAYYKLRH IVDEVNGLIS MYSTDENLIL
310 320 330 340 350 360
SPLLGNVCFS SSQYSICFTL GSFAKIYADT FGDINYQEFA KRLWGDIYFN PKTRKFTKKA
370 380 390 400 410 420
PTSSSQRSFV EFILEPLYKI LAQVVGDVDT SLPRTLDELG IHLTKEELKL NIRPLLRLVC
430 440 450 460 470 480
KKFFGEFTGF VDMCVQHIPS PKVGAKPKIE HTYTGGVDSD LGEAMSDCDP DGPLMCHTTK
490 500 510 520 530 540
MYSTDDGVQF HAFGRVLSGT IHAGQPVKVL GENYTLEDEE DSQICTVGRL WISVARYHIE
550 560 570 580 590 600
VNRVPAGNWV LIEGVDQPIV KTATITEPRG NEEAQIFRPL KFNTTSVIKI AVEPVNPSEL
610 620 630 640 650 660
PKMLDGLRKV NKSYPSLTTK VEESGEHVIL GTGELYLDCV MHDLRKMYSE IDIKVADPVV
670 680 690 700 710 720
TFCETVVETS SLKCFAETPN KKNKITMIAE PLEKGLAEDI ENEVVQITWN RKKLGEFFQT
730 740 750 760 770 780
KYDWDLLAAR SIWAFGPDAT GPNILVDDTL PSEVDKALLG SVKDSIVQGF QWGTREGPLC
790 800 810 820 830 840
DELIRNVKFK ILDAVVAQEP LHRGGGQIIP TARRVVYSAF LMATPRLMEP YYFVEVQAPA
850 860 870 880 890 900
DCVSAVYTVL ARRRGHVTQD APIPGSPLYT IKAFIPAIDS FGFETDLRTH TQGQAFSLSV
910 920 930 940 950 960
FHHWQIVPGD PLDKSIVIRP LEPQPAPHLA REFMIKTRRR KGLSEDVSIS KFFDDPMLLE
970
LAKQDVVLNY PM
Isoforms
- Isoform 2 of 116 kDa U5 small nuclear ribonucleoprotein component - Isoform 3 of 116 kDa U5 small nuclear ribonucleoprotein componentSequence View
10 20 30 40 50 60
MDTDLYDEFG NYIGPELDSD EDDDELGRET KDLDEMDDDD DDDDVGDHDD DHPGMEVVLH
70 80 90 100 110 120
EDKKYYPTAE EVYGPEVETI VQEEDTQPLT EPIIKPVKTK KFTLMEQTLP VTVYEMDFLA
130 140 150 160 170 180
DLMDNSELIR NVTLCGHLHH GKTCFVDCLI EQTHPEIRKR YDQDLCYTDI LFTEQERGVG
190 200 210 220 230 240
IKSTPVTVVL PDTKGKSYLF NIMDTPGHVN FSDEVTAGLR ISDGVVLFID AAEGVMLNTE
250 260 270 280 290 300
RLIKHAVQER LAVTVCINKI DRLILELKLP PTDAYYKLRH IVDEVNGLIS MYSTDENLIL
310 320 330 340 350 360
SPLLGNVCFS SSQYSICFTL GSFAKIYADT FGDINYQEFA KRLWGDIYFN PKTRKFTKKA
370 380 390 400 410 420
PTSSSQRSFV EFILEPLYKI LAQVVGDVDT SLPRTLDELG IHLTKEELKL NIRPLLRLVC
430 440 450 460 470 480
KKFFGEFTGF VDMCVQHIPS PKVGAKPKIE HTYTGGVDSD LGEAMSDCDP DGPLMCHTTK
490 500 510 520 530 540
MYSTDDGVQF HAFGRVLSGT IHAGQPVKVL GENYTLEDEE DSQICTVGRL WISVARYHIE
550 560 570 580 590 600
VNRVPAGNWV LIEGVDQPIV KTATITEPRG NEEAQIFRPL KFNTTSVIKI AVEPVNPSEL
610 620 630 640 650 660
PKMLDGLRKV NKSYPSLTTK VEESGEHVIL GTGELYLDCV MHDLRKMYSE IDIKVADPVV
670 680 690 700 710 720
TFCETVVETS SLKCFAETPN KKNKITMIAE PLEKGLAEDI ENEVVQITWN RKKLGEFFQT
730 740 750 760 770 780
KYDWDLLAAR SIWAFGPDAT GPNILVDDTL PSEVDKALLG SVKDSIVQGF QWGTREGPLC
790 800 810 820 830 840
DELIRNVKFK ILDAVVAQEP LHRGGGQIIP TARRVVYSAF LMATPRLMEP YYFVEVQAPA
850 860 870 880 890 900
DCVSAVYTVL ARRRGHVTQD APIPGSPLYT IKAFIPAIDS FGFETDLRTH TQGQAFSLSV
910 920 930 940 950 960
FHHWQIVPGD PLDKSIVIRP LEPQPAPHLA REFMIKTRRR KGLSEDVSIS KFFDDPMLLE
970
LAKQDVVLNY PM
10 20 30 40 50 60
MDTDLYDEFG NYIGPELDSD EDDDELGRET KDLDEMDDDD DDDDVGDHDD DHPGMEVVLH
70 80 90 100 110 120
EDKKYYPTAE EVYGPEVETI VQEEDTQPLT EPIIKPVKTK KFTLMEQTLP VTVYEMDFLA
130 140 150 160 170 180
DLMDNSELIR NVTLCGHLHH GKTCFVDCLI EQTHPEIRKR YDQDLCYTDI LFTEQERGVG
190 200 210 220 230 240
IKSTPVTVVL PDTKGKSYLF NIMDTPGHVN FSDEVTAGLR ISDGVVLFID AAEGVMLNTE
250 260 270 280 290 300
RLIKHAVQER LAVTVCINKI DRLILELKLP PTDAYYKLRH IVDEVNGLIS MYSTDENLIL
310 320 330 340 350 360
SPLLGNVCFS SSQYSICFTL GSFAKIYADT FGDINYQEFA KRLWGDIYFN PKTRKFTKKA
370 380 390 400 410 420
PTSSSQRSFV EFILEPLYKI LAQVVGDVDT SLPRTLDELG IHLTKEELKL NIRPLLRLVC
430 440 450 460 470 480
KKFFGEFTGF VDMCVQHIPS PKVGAKPKIE HTYTGGVDSD LGEAMSDCDP DGPLMCHTTK
490 500 510 520 530 540
MYSTDDGVQF HAFGRVLSGT IHAGQPVKVL GENYTLEDEE DSQICTVGRL WISVARYHIE
550 560 570 580 590 600
VNRVPAGNWV LIEGVDQPIV KTATITEPRG NEEAQIFRPL KFNTTSVIKI AVEPVNPSEL
610 620 630 640 650 660
PKMLDGLRKV NKSYPSLTTK VEESGEHVIL GTGELYLDCV MHDLRKMYSE IDIKVADPVV
670 680 690 700 710 720
TFCETVVETS SLKCFAETPN KKNKITMIAE PLEKGLAEDI ENEVVQITWN RKKLGEFFQT
730 740 750 760 770 780
KYDWDLLAAR SIWAFGPDAT GPNILVDDTL PSEVDKALLG SVKDSIVQGF QWGTREGPLC
790 800 810 820 830 840
DELIRNVKFK ILDAVVAQEP LHRGGGQIIP TARRVVYSAF LMATPRLMEP YYFVEVQAPA
850 860 870 880 890 900
DCVSAVYTVL ARRRGHVTQD APIPGSPLYT IKAFIPAIDS FGFETDLRTH TQGQAFSLSV
910 920 930 940 950 960
FHHWQIVPGD PLDKSIVIRP LEPQPAPHLA REFMIKTRRR KGLSEDVSIS KFFDDPMLLE
970
LAKQDVVLNY PM
Protein Neighborhood
Domains & Features
8 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q15029-1-Acetylation | MDTDLY... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q15029-1-Acetylation | MDTDLY... | 1 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
Q15029-36-unknown | MDDDDD... | 36 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt93524 | |||
Q15029-170-unknown | ILFTEQ... | 170 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12335 | |||
Q15029-170-unknown | ILFTEQ... | 170 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt144065 | |||
Q15029-384-unknown | VVGDVD... | 384 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4061 | |||
Q15029-384-unknown | VVGDVD... | 384 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt150925 | |||
Q15029-499-unknown | GTIHAG... | 499 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7851 | |||
Q15029-499-unknown | GTIHAG... | 499 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152970 | |||
Q15029-500-unknown | TIHAGQ... | 500 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4063 | |||
Q15029-500-unknown | TIHAGQ... | 500 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152982 | |||
Q15029-919-unknown | RPLEPQ... | 919 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6437 | |||
Q15029-919-unknown | RPLEPQ... | 919 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156802 | |||
Q15029-955-unknown | DPMLLE... | 955 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17953 | |||
Q15029-955-unknown | DPMLLE... | 955 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156966 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LCYTDI | 169 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC12335 | |||
...LCYTDI | 169 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt127316 | |||
...KILAQV | 383 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4061 | |||
...KILAQV | 383 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt134327 | |||
...GRVLSG | 498 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC7851 | |||
...GRVLSG | 498 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136396 | |||
...RVLSGT | 499 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4063 | |||
...RVLSGT | 499 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136408 | |||
...KSIVIR | 918 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6437 | |||
...KSIVIR | 918 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140295 | |||
...SKFFDD | 954 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC17953 | |||
...SKFFDD | 954 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140457 | |||
...LNYPM | 972 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...LNYPM | 972 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt89142 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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