Q15293: Reticulocalbin-1

General Information

Protein names	- Reticulocalbin-1
Gene names	RCN1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15293

5 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MARGGRGRRL GLALGLLLAL VLAPRVLRAK PTVRKERVVR PDSELGERPP EDNQSFQYDH
        70         80         90        100        110        120
EAFLGKEDSK TFDQLTPDES KERLGKIVDR IDNDGDGFVT TEELKTWIKR VQKRYIFDNV
       130        140        150        160        170        180
AKVWKDYDRD KDDKISWEEY KQATYGYYLG NPAEFHDSSD HHTFKKMLPR DERRFKAADL
       190        200        210        220        230        240
NGDLTATREE FTAFLHPEEF EHMKEIVVLE TLEDIDKNGD GFVDQDEYIA DMFSHEENGP
       250        260        270        280        290        300
EPDWVLSERE QFNEFRDLNK DGKLDKDEIR HWILPQDYDH AQAEARHLVY ESDKNKDEKL
       310        320        330
TKEEILENWN MFVGSQATNY GEDLTKNHDE L

Isoforms

- Isoform 2 of Reticulocalbin-1

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q15293-30-unknown	KPTVRK...	30	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15293-167-unknown	MLPRDE...	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436482
Q15293-196-unknown	HPEEFE...	196	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17982
Q15293-232-unknown	MFSHEE...	232	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1305
Q15293-304-unknown	EILENW...	304	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433237

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FTAFLH	195	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17982
...DGFVDQ	224	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436482
...EYIADM	231	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1305
...NHDEL	331	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	195	AFLH.\|.HPEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP1_HUMAN	231	IADM.\|.MFSH	inferred from experiment	unknown	MEROPS	Wells JA	Agard NJ et al.:Inflammatory stimuli regulate c... (C14.001)	20173201,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)