Q96AE4: Far upstream element-binding protein 1

General Information

Protein names	- Far upstream element-binding protein 1 - FBP - FUSE-binding protein 1 - DNA helicase V - hDH V
Gene names	FUBP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96AE4

31 N-termini

9 C-termini

11 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADYSTVPPP SSGSAGGGGG GGGGGGVNDA FKDALQRARQ IAAKIGGDAG TSLNSNDYGY
        70         80         90        100        110        120
GGQKRPLEDG DQPDAKKVAP QNDSFGTQLP PMHQQQSRSV MTEEYKVPDG MVGFIIGRGG
       130        140        150        160        170        180
EQISRIQQES GCKIQIAPDS GGLPERSCML TGTPESVQSA KRLLDQIVEK GRPAPGFHHG
       190        200        210        220        230        240
DGPGNAVQEI MIPASKAGLV IGKGGETIKQ LQERAGVKMV MIQDGPQNTG ADKPLRITGD
       250        260        270        280        290        300
PYKVQQAKEM VLELIRDQGG FREVRNEYGS RIGGNEGIDV PIPRFAVGIV IGRNGEMIKK
       310        320        330        340        350        360
IQNDAGVRIQ FKPDDGTTPE RIAQITGPPD RCQHAAEIIT DLLRSVQAGN PGGPGPGGRG
       370        380        390        400        410        420
RGRGQGNWNM GPPGGLQEFN FIVPTGKTGL IIGKGGETIK SISQQSGARI ELQRNPPPNA
       430        440        450        460        470        480
DPNMKLFTIR GTPQQIDYAR QLIEEKIGGP VNPLGPPVPH GPHGVPGPHG PPGPPGPGTP
       490        500        510        520        530        540
MGPYNPAPYN PGPPGPAPHG PPAPYAPQGW GNAYPHWQQQ APPDPAKAGT DPNSAAWAAY
       550        560        570        580        590        600
YAHYYQQQAQ PPPAAPAGAP TTTQTNGQGD QQNPAPAGQV DYTKAWEEYY KKMGQAVPAP
       610        620        630        640
TGAPPGGQPD YSAAWAEYYR QQAAYYAQTS PQGMPQHPPA PQGQ

Isoforms

- Isoform 2 of Far upstream element-binding protein 1

Sequence View

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Protein Neighborhood

Domains & Features

31 N-termini - 9 C-termini - 11 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96AE4-1-unknown	MADYST...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt75527
Q96AE4-2-unknown	MADYST...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96AE4-2-Acetylation	ADYSTV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96AE4-2-Acetylation	ADYSTV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q96AE4-2-Acetylation	ADYSTV...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111460
Q96AE4-14-unknown	SAGGGG...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4184
Q96AE4-14-unknown	SAGGGG...	14		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt136469
Q96AE4-77-unknown	KVAPQN...	77			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96AE4-77-	KVAPQN...	77			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q96AE4-78-	VAPQND...	78			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96AE4-84-	SFGTQL...	84			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q96AE4-88-unknown	QLPPMH...	88		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q96AE4-99-unknown	SVMTEE...	99		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171241
Q96AE4-99-	SVMTEE...	99			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96AE4-99-	SVMTEE...	99			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q96AE4-102-unknown	TEEYKV...	102		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19728
Q96AE4-102-unknown	TEEYKV...	102		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18071
Q96AE4-102-unknown	TEEYKV...	102		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197011
Q96AE4-103-unknown	EEYKVP...	103		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19729
Q96AE4-103-unknown	EEYKVP...	103		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197035
Q96AE4-129-unknown	ESGCKI...	129		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19730
Q96AE4-129-unknown	ESGCKI...	129		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18072
Q96AE4-129-unknown	ESGCKI...	129		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143798
Q96AE4-182-unknown	GPGNAV...	182		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165476
Q96AE4-182-	GPGNAV...	182			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96AE4-182-	GPGNAV...	182			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96AE4-184-unknown	GNAVQE...	184			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96AE4-184-unknown	GNAVQE...	184		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161573
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q96AE4-184-	GNAVQE...	184			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q96AE4-186-unknown	AVQEIM...	186		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173643
Q96AE4-186-	AVQEIM...	186			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96AE4-186-	AVQEIM...	186			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q96AE4-197-	AGLVIG...	197			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q96AE4-197-unknown	AGLVIG...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177223
Q96AE4-222-unknown	IQDGPQ...	222		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6650
Q96AE4-222-unknown	IQDGPQ...	222		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147409
Q96AE4-224-unknown	DGPQNT...	224		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8001
Q96AE4-224-unknown	DGPQNT...	224		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6652
Q96AE4-224-unknown	DGPQNT...	224		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt147473
Q96AE4-345-unknown	SVQAGN...	345		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177860
Q96AE4-345-	SVQAGN...	345			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q96AE4-378-unknown	EFNFIV...	378		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19732
Q96AE4-378-unknown	EFNFIV...	378		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt151552
Q96AE4-388-unknown	TGLIIG...	388			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96AE4-388-unknown	TGLIIG...	388		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161578
Q96AE4-449-unknown	GPVNPL...	449		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6654
Q96AE4-449-unknown	GPVNPL...	449		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt152775
Q96AE4-567-	GQGDQQ...	567			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q96AE4-567-	GQGDQQ...	567			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q96AE4-567-	GQGDQQ...	567			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96AE4-567-	GQGDQQ...	567			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96AE4-567-	GQGDQQ...	567			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q96AE4-567-unknown	GQGDQQ...	567			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q96AE4-567-unknown	GQGDQQ...	567		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161575

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PPSSGS	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4184
...SRSVMT	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19728
...SRSVMT	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18071
...RSVMTE	102	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19729
...SRIQQE	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19730
...SRIQQE	128	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18072
...SRIQQE	128	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127040
...VKMVMI	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6650
...VKMVMI	221	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130758
...MVMIQD	223	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8001
...MVMIQD	223	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6652
...MVMIQD	223	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt130823
...PGGLQE	377	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19732
...PGGLQE	377	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134957
...EEKIGG	448	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6654
...EEKIGG	448	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt136196
...APQGQ	644	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	13	SSGS.\|.SAGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	101	SVMT.\|.TEEY	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	101	SVMT.\|.TEEY	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	102	VMTE.\|.EEYK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	128	IQQE.\|.ESGC	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	128	IQQE.\|.ESGC	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	221	MVMI.\|.IQDG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	223	MIQD.\|.DGPQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATL1_HUMAN	223	MIQD.\|.DGPQ	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	377	GLQE.\|.EFNF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	448	KIGG.\|.GPVN	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)