P02533: Keratin, type I cytoskeletal 14

General Information

Protein names	- Keratin, type I cytoskeletal 14 - Cytokeratin-14 - CK-14 - Keratin-14 - K14
Gene names	KRT14
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02533

5 N-termini

5 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTTCSRQFTS SSSMKGSCGI GGGIGGGSSR ISSVLAGGSC RAPSTYGGGL SVSSSRFSSG
        70         80         90        100        110        120
GACGLGGGYG GGFSSSSSSF GSGFGGGYGG GLGAGLGGGF GGGFAGGDGL LVGSEKVTMQ
       130        140        150        160        170        180
NLNDRLASYL DKVRALEEAN ADLEVKIRDW YQRQRPAEIK DYSPYFKTIE DLRNKILTAT
       190        200        210        220        230        240
VDNANVLLQI DNARLAADDF RTKYETELNL RMSVEADING LRRVLDELTL ARADLEMQIE
       250        260        270        280        290        300
SLKEELAYLK KNHEEEMNAL RGQVGGDVNV EMDAAPGVDL SRILNEMRDQ YEKMAEKNRK
       310        320        330        340        350        360
DAEEWFFTKT EELNREVATN SELVQSGKSE ISELRRTMQN LEIELQSQLS MKASLENSLE
       370        380        390        400        410        420
ETKGRYCMQL AQIQEMIGSV EEQLAQLRCE MEQQNQEYKI LLDVKTRLEQ EIATYRRLLE
       430        440        450        460        470
GEDAHLSSSQ FSSGSQSSRD VTSSSRQIRT KVMDVHDGKV VSTHEQVLRT KN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P02533-1-unknown	MTTCSR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P02533-302-unknown	AEEWFF...	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17025
P02533-302-unknown	AEEWFF...	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18366
P02533-303-unknown	EEWFFT...	303	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18367
P02533-454-unknown	DVHDGK...	454	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17026
P02533-454-unknown	DVHDGK...	454	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18368
P02533-457-unknown	DGKVVS...	457	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17027
P02533-457-unknown	DGKVVS...	457	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18369

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KNRKDA	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17025
...KNRKDA	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18366
...NRKDAE	302	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18367
...RTKVMD	453	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17026
...RTKVMD	453	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18368
...VMDVHD	456	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17027
...VMDVHD	456	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18369
...LRTKN	472	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	301	RKDA.\|.AEEW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	301	RKDA.\|.AEEW	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	302	KDAE.\|.EEWF	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	453	KVMD.\|.DVHD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	453	KVMD.\|.DVHD	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	456	DVHD.\|.DGKV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	456	DVHD.\|.DGKV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)